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淋巴水肿 - 丝虫病还是软组织肉瘤?一例报告。

Lymphoedema - Filariasis or soft tissue sarcoma? A case report.

作者信息

Sarinah Tamring, Zanaridah Mat Nawi, Nik Farah Nik Yusof Fuad, Tham Joon Hi, Shahrunizam Mohamad Setia Awang

机构信息

MD, Klinik Kesihatan Putatan, Jalan Pasir Putih, Putatan, Sabah, Malaysia. E-mail:

MBBS, Dr. Fam. Med, Klinik Kesihatan Putatan, Jalan Pasir Putih, Putatan, Sabah, Malaysia.

出版信息

Malays Fam Physician. 2025 Jul 29;20:51. doi: 10.51866/cr.877. eCollection 2025.

DOI:10.51866/cr.877
PMID:40787663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12334323/
Abstract

This is a case report of a middle-aged man who presented with chronic unilateral lower limb swelling and a mass on the same side. Several important differential diagnoses were considered. Lymphatic filariasis was included in the differential diagnoses due to a history of travel to a district endemic with filariasis in Sabah. A final diagnosis of soft tissue sarcoma was provisionally made based on the magnetic resonance imaging findings and confirmed by histopathological examination as pleomorphic dermal sarcoma. Both conditions are unusual but important causes in primary care due to their association with poor morbidity and risk of mortality. Patient management should involve a multidisciplinary team, including primary care, public health, radiology, pathology and orthopaedics.

摘要

这是一例中年男性病例报告,该患者出现慢性单侧下肢肿胀及同侧肿物。考虑了几种重要的鉴别诊断。由于有前往沙巴州丝虫病流行地区旅行的病史,淋巴丝虫病被纳入鉴别诊断。根据磁共振成像结果初步诊断为软组织肉瘤,并经组织病理学检查确诊为多形性皮肤肉瘤。这两种情况虽不常见,但在基层医疗中却是重要病因,因为它们与高发病率和死亡风险相关。患者管理应涉及多学科团队,包括基层医疗、公共卫生、放射学、病理学和骨科学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/e2d3590e9dd4/MFP-20-51-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/0d3f2ce8a5d6/MFP-20-51-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/e8ce6d356105/MFP-20-51-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/f11945118104/MFP-20-51-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/8bf0143a4ece/MFP-20-51-g4a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/e2d3590e9dd4/MFP-20-51-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/0d3f2ce8a5d6/MFP-20-51-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/e8ce6d356105/MFP-20-51-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/f11945118104/MFP-20-51-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/8bf0143a4ece/MFP-20-51-g4a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/12334323/e2d3590e9dd4/MFP-20-51-g5.jpg

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本文引用的文献

1
UK guidelines for the management of soft tissue sarcomas.英国软组织肉瘤管理指南。
Br J Cancer. 2025 Jan;132(1):11-31. doi: 10.1038/s41416-024-02674-y. Epub 2024 May 11.
2
Case series of high-grade soft tissue sarcoma of the lower limb with delayed diagnosis: Experience at a tertiary hospital in northern Tanzania.下肢高级别软组织肉瘤延迟诊断的病例系列:坦桑尼亚北部一家三级医院的经验
Int J Surg Case Rep. 2022 Aug;97:107475. doi: 10.1016/j.ijscr.2022.107475. Epub 2022 Aug 2.
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Soft Tissue Masses: Evaluation and Treatment.软组织肿块:评估与治疗。
Am Fam Physician. 2022 Jun 1;105(6):602-612.
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Clinical and Pathological Characteristics of Soft Tissue Sarcomas: A Retrospective Study From a Developing Country.软组织肉瘤的临床和病理特征:一项来自发展中国家的回顾性研究
Cureus. 2020 Aug 21;12(8):e9913. doi: 10.7759/cureus.9913.
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Limited biopsies of soft tissue tumors: the contemporary role of immunohistochemistry and molecular diagnostics.软组织肿瘤的有限活检:免疫组织化学和分子诊断的当代作用。
Mod Pathol. 2019 Jan;32(Suppl 1):27-37. doi: 10.1038/s41379-018-0139-y. Epub 2019 Jan 2.