Nakano M, Iida K, Sato S, Sakata S, Sueyama H
Gan No Rinsho. 1985 Sep;31(12):1602-4.
Relationship between irradiated dose and function preservation of the larynx in patients of laryngeal carcinoma (T1-T3) treated with radiotherapy were analysed and discussed. Local control rate for T1 and T2 lesion was highest in the dose range of 65-70 Gy. But in T3 lesion, especially of supraglottic cancer, the dose range to obtain highest local tumor control rate is above 76 Gy and higher than in case of T1 and T2 lesions. Laryngeal edema was seen in patients who were delivered the dose of 80 Gy. But total laryngectomy could be avoided by conservative therapy. Necessity of induction chemotherapy for advanced cases was also discussed.
分析并讨论了喉癌（T1-T3）患者接受放射治疗时照射剂量与喉功能保留之间的关系。T1和T2病变的局部控制率在65-70 Gy剂量范围内最高。但在T3病变中，尤其是声门上癌，获得最高局部肿瘤控制率的剂量范围高于76 Gy，且高于T1和T2病变。接受80 Gy剂量的患者出现了喉水肿。但通过保守治疗可避免全喉切除术。还讨论了晚期病例诱导化疗的必要性。
