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[癌症放射治疗标准化与优化的放射生物学考量]

[Radiobiological consideration for standardization and optimization in radiotherapy on cancers].

作者信息

Sakamoto K

出版信息

Gan No Rinsho. 1985 Sep;31(12):1639-41.

PMID:4079055
Abstract

It is so important for standardization and optimization in radiotherapy on cancers to estimate accurately target volume for irradiation and radiation injury on normal tissues. It is responsible for radiation diagnosticians to determine target volume, but in order to estimate late injuries on normal tissues radiobiological research is seemed to be useful. Concerning normal tissue damage, it is very difficult to forecast late damages on various sort of normal tissues from the standpoint of radiobiology in course of radiotherapy. To dissolve this problem it is needed to develop new biological model systems and to find new marker to forecast late injuries from acute damages. In this paper it is also discussed for establishment of radiation oncology in Japan.

摘要

在癌症放射治疗中,准确估计照射靶区体积和正常组织的放射损伤对于标准化和优化治疗至关重要。确定靶区体积是放射诊断医生的职责,但为了估计正常组织的晚期损伤,放射生物学研究似乎很有用。关于正常组织损伤,从放射生物学角度在放射治疗过程中预测各种正常组织的晚期损伤非常困难。为了解决这个问题,需要开发新的生物学模型系统并找到预测晚期损伤与急性损伤的新标志物。本文还讨论了日本放射肿瘤学的建立。

相似文献

1
[Radiobiological consideration for standardization and optimization in radiotherapy on cancers].[癌症放射治疗标准化与优化的放射生物学考量]
Gan No Rinsho. 1985 Sep;31(12):1639-41.
2
Radiobiological models of normal tissue reactions.正常组织反应的放射生物学模型。
Strahlenther Onkol. 1998 Nov;174 Suppl 3:4-7.
3
[Standardization and optimization of the radiotherapy schedule from the standpoint of the tolerance dose of the normal tissues].从正常组织耐受剂量角度看放射治疗计划的标准化与优化
Gan No Rinsho. 1985 Sep;31(12):1512-9.
4
Adverse event reporting and developments in radiation biology after normal tissue injury: International Atomic Energy Agency consultation.正常组织损伤后不良事件报告及放射生物学进展:国际原子能机构磋商会
Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1442-51. doi: 10.1016/j.ijrobp.2005.10.014. Epub 2006 Jan 18.
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[Physical problems as to standardization and optimization of radiation therapy].[放射治疗标准化与优化中的物理问题]
Gan No Rinsho. 1985 Sep;31(12):1490-5.
6
Compensation of missed fractions without knowledge of radiobiological parameters.在不了解放射生物学参数的情况下对漏照分次剂量进行补偿。
Med Dosim. 2011 Winter;36(4):429-33. doi: 10.1016/j.meddos.2010.10.005. Epub 2011 Mar 11.
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Simultaneous beam geometry and intensity map optimization in intensity-modulated radiation therapy.调强放射治疗中射束几何形状与强度图的同步优化
Int J Radiat Oncol Biol Phys. 2006 Jan 1;64(1):301-20. doi: 10.1016/j.ijrobp.2005.08.023. Epub 2005 Nov 14.
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TCP and NTCP in preclinical and clinical research in Europe.欧洲临床前和临床研究中的TCP与NTCP
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9
Regarding: Rosenthal DI, Glatstein E. "We've Got a Treatment, but What's the Disease?" The Oncologist 1996;1.关于:罗森塔尔·迪、格拉茨坦·埃。《我们有了一种治疗方法,但疾病是什么?》,《肿瘤学家》1996年;第1期。
Oncologist. 1997;2(1):59-61.
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[Interactive determination of the parameters of mathematical models for planning radiotherapy of malignant tumors. I. Mathematical models for calculating dose tolerance, adequate doses and the likelihood of development of radiation complications in normal organs and tissues].[恶性肿瘤放射治疗计划数学模型参数的交互式确定。I. 计算正常器官和组织中剂量耐受性、适宜剂量及放射并发症发生可能性的数学模型]
Med Tekh. 2000 Jul-Aug(4):37-41.

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