Shatalin Daniel, Levenfus Kateryna, Weiss Adina, Grisaru-Granovsky Sorina, Gozal Yaacov, Ronenson Alexander, Ioscovich Alexander
Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, affiliated with Hebrew University, Jerusalem, Israel.
Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel.
Clin Appl Thromb Hemost. 2025 Jan-Dec;31:10760296251367722. doi: 10.1177/10760296251367722. Epub 2025 Aug 11.
Background and AimsThromboelastography (TEG) is a non-invasive, readily available quantitative test used to assess the clotting ability of whole blood. In this study, we aim to explore the indications for utilizing TEG during the peripartum period.MethodsA single-center, retrospective study was conducted, analyzing the electronic medical records of 288 women admitted to the labor and delivery unit, all of whom underwent TEG testing. The study period was five years. Data collected encompassed various hematological parameters; and TEG parameters with a focus on maximum amplitude (MA) were recorded. Furthermore, the diagnoses prompting TEG referral were documented for each participant.ResultsAll participants were categorized into one of the following six groups: gestational thrombocytopenia (n = 41, 14.24%), immune thrombocytopenic purpura (ITP) (n = 33, 11.46%), preeclampsia (n = 27, 9.38%), preexisting coagulopathy (n = 14, 4.86%), suspected coagulopathy (n = 26, 9.03%), and massive bleeding (n = 147, 51.04%). TEG results indicated that MA values were within the normal range for the majority of participants in each category. Regional anesthesia was performed across all groups, with the following distribution: gestational thrombocytopenia (73.17%), ITP (36.36%), preeclampsia (62.96%), preexisting coagulopathy (64.29%), suspected coagulopathy (53.85%), and massive bleeding (65.46%).ConclusionsWe identified two primary reasons for performing TEG during the peripartum period: low platelet count and massive bleeding. TEG, particularly the MA parameter, plays a valuable role in peripartum management, particularly in guiding decisions regarding the suitability of neuraxial anesthesia in the presence of a low platelet count and in directing the administration of blood products in cases of massive bleeding.
背景与目的
血栓弹力图(TEG)是一种用于评估全血凝血能力的非侵入性、易于获取的定量检测方法。在本研究中,我们旨在探讨围产期使用TEG的指征。
方法
进行了一项单中心回顾性研究,分析了288名入住分娩单元的女性的电子病历,所有这些女性均接受了TEG检测。研究期为五年。收集的数据包括各种血液学参数;并记录了以最大振幅(MA)为重点的TEG参数。此外,记录了促使每个参与者进行TEG检测的诊断情况。
结果
妊娠期血小板减少症(n = 41,14.24%)、免疫性血小板减少性紫癜(ITP)(n = 33,11.46%)、先兆子痫(n = 27,9.38%)、既往存在的凝血病(n = 14,4.86%)、疑似凝血病(n = 26,9.03%)和大量出血(n = 147,51.04%)。TEG结果表明,各类别中大多数参与者的MA值在正常范围内。所有组均进行了区域麻醉,分布如下:妊娠期血小板减少症(73.17%)、ITP(36.36%)、先兆子痫(62.96%)、既往存在的凝血病(64.29%)、疑似凝血病(53.85%)和大量出血(65.46%)。
结论
我们确定了围产期进行TEG检测的两个主要原因:血小板计数低和大量出血。TEG,尤其是MA参数,在围产期管理中发挥着重要作用,特别是在指导血小板计数低时关于神经轴麻醉适用性的决策以及在大量出血情况下指导血液制品的输注方面。