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Impaired modulation of the trigeminal caudal nucleus by the locus coeruleus in diabetic mice: the role of GABAergic and glycinergic neurons.

作者信息

Mesa-Lombardo Alberto, García-Magro Nuria, Nuñez Angel, Martin Yasmina B

机构信息

Department of Anatomy, Histology and Neurosciences, Universidad Autónoma de Madrid, Madrid, Spain.

Facultad de Ciencias de la Salud, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Madrid, Spain.

出版信息

Front Neuroanat. 2025 Jul 28;19:1600026. doi: 10.3389/fnana.2025.1600026. eCollection 2025.

DOI:10.3389/fnana.2025.1600026
PMID:40791852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12336202/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/8c1ce0811b5c/fnana-19-1600026-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/be9484dde2b7/fnana-19-1600026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/07c6c9316d5b/fnana-19-1600026-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/2d4622055efb/fnana-19-1600026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/837f1dbba3af/fnana-19-1600026-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/3453b80cf703/fnana-19-1600026-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/600de91e4071/fnana-19-1600026-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/35719647d19e/fnana-19-1600026-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/9c27e9f03f7e/fnana-19-1600026-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/65063cba111c/fnana-19-1600026-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/8c1ce0811b5c/fnana-19-1600026-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/be9484dde2b7/fnana-19-1600026-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/07c6c9316d5b/fnana-19-1600026-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/2d4622055efb/fnana-19-1600026-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/837f1dbba3af/fnana-19-1600026-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/3453b80cf703/fnana-19-1600026-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/600de91e4071/fnana-19-1600026-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/35719647d19e/fnana-19-1600026-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/9c27e9f03f7e/fnana-19-1600026-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/65063cba111c/fnana-19-1600026-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b905/12336202/8c1ce0811b5c/fnana-19-1600026-g010.jpg

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本文引用的文献

1
The Locus Coeruleus in Chronic Pain.蓝斑在慢性疼痛中的作用。
Int J Mol Sci. 2024 Aug 8;25(16):8636. doi: 10.3390/ijms25168636.
2
Distinct neural activities of the cortical layer 2/3 across isoflurane anesthesia: A large-scale simultaneous observation of neurons.皮层第 2/3 层在异氟烷麻醉下的不同神经活动：神经元的大规模同步观察。
Biomed Pharmacother. 2024 Jun;175:116751. doi: 10.1016/j.biopha.2024.116751. Epub 2024 May 15.
3
Locus coeruleus inhibition of vibrissal responses in the trigeminal subnucleus caudalis are reduced in a diabetic mouse model.
在糖尿病小鼠模型中，蓝斑对三叉神经尾侧亚核中触须反应的抑制作用减弱。
Front Cell Neurosci. 2023 Jul 5;17:1208121. doi: 10.3389/fncel.2023.1208121. eCollection 2023.
4
Locus coeruleus-noradrenergic modulation of trigeminal pain: Implications for trigeminal neuralgia and psychiatric comorbidities.蓝斑-去甲肾上腺素能对三叉神经痛的调节作用：对三叉神经痛及精神共病的影响
Neurobiol Pain. 2023 Mar 20;13:100124. doi: 10.1016/j.ynpai.2023.100124. eCollection 2023 Jan-Jul.
5
GABAergic signalling in modulation of dental pain.GABA 能系统在调节牙痛中的作用。
Eur J Pharmacol. 2022 Jun 5;924:174958. doi: 10.1016/j.ejphar.2022.174958. Epub 2022 Apr 14.
6
The trigeminal pathways.三叉神经通路。
J Neurol. 2022 Jul;269(7):3443-3460. doi: 10.1007/s00415-022-11002-4. Epub 2022 Mar 6.
7
Glycine Receptors in Spinal Nociceptive Control-An Update.脊髓伤害性控制中的甘氨酸受体——更新。
Biomolecules. 2021 Jun 6;11(6):846. doi: 10.3390/biom11060846.
8
Microglia and Inhibitory Circuitry in the Medullary Dorsal Horn: Laminar and Time-Dependent Changes in a Trigeminal Model of Neuropathic Pain.牙髓神经病理性疼痛模型中背角浅层的小胶质细胞和抑制性回路：时程和层依赖性变化。
Int J Mol Sci. 2021 Apr 27;22(9):4564. doi: 10.3390/ijms22094564.
9
Streptozotocin-Induced Diabetic Models in Mice and Rats.链脲佐菌素诱导的小鼠和大鼠糖尿病模型。
Curr Protoc. 2021 Apr;1(4):e78. doi: 10.1002/cpz1.78.
10
α-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition.神经传递、突触可塑性和认知中的α-肾上腺素能受体
Front Pharmacol. 2020 Sep 29;11:581098. doi: 10.3389/fphar.2020.581098. eCollection 2020.