Cohen L, Kitzes R, Shnaider H
Magnesium. 1985;4(4):176-81.
A group of 8 patients with essential hypertension and 12 patients with recurrent renal calcium stones were treated with 50 mg hydrochlorothiazide daily for a period of 3-10 years. Serum, erythrocyte, lymphocyte, skeletal muscle, bone and urine Mg were found to be within the normal range. In the intravenous Mg load test, all patients retained a normal percentage of the loading dose of Mg. Long-term thiazide therapy does not appear to lead to Mg depletion.
一组8例原发性高血压患者和12例复发性肾钙结石患者，每天服用50毫克氢氯噻嗪，治疗3至10年。发现血清、红细胞、淋巴细胞、骨骼肌、骨骼和尿液中的镁含量均在正常范围内。在静脉注射镁负荷试验中，所有患者保留的镁负荷剂量百分比均正常。长期噻嗪类药物治疗似乎不会导致镁缺乏。
