Chou Fu-Sheng, Yeh Hung-Wen, Hsueh Crystal, Zhang Jing, Villosis Maria Fe B, Barseghyan Karine, Lakshmanan Ashwini, Clark Reese H
Southern California Permanente Medical Group, Pasadena, CA, USA.
Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
J Perinatol. 2025 Aug 12. doi: 10.1038/s41372-025-02374-2.
To categorize growth and correlate growth categories with morbidities in infants born before 32 weeks of gestation.
This retrospective study categorized weight growth by correlating mean growth velocity (GV) with growth trajectory z-score changes ( ), as measured using 2023 Postnatal Growth Charts for Preterm Infants. The associations between weight categories and morbidities were assessed.
Weight gain of infants without morbidities was categorized into three groups based on correlating with mean GV: slower ( < -0.1), in-parallel ( -0.1 to 0.3), and faster ( > 0.3). The proportions of infants with and without morbidities in these categories were evaluated across two distinct cohorts, revealing similar patterns. Both slower and faster growth were associated with bronchopulmonary dysplasia, while only slower growth was associated with retinopathy of prematurity.
Using the 2023 Postnatal Growth Charts for Preterm Infants, this study presents an alternative method for weight growth categorization.
对妊娠32周前出生的婴儿的生长情况进行分类,并将生长类别与发病率相关联。
这项回顾性研究通过将平均生长速度(GV)与生长轨迹z评分变化( )相关联来对体重增长进行分类,生长轨迹z评分变化使用2023年早产儿产后生长图表进行测量。评估了体重类别与发病率之间的关联。
根据 与平均GV的相关性,将无疾病婴儿的体重增加分为三组:较慢( < -0.1)、平行( -0.1至0.3)和较快( > 0.3)。在两个不同队列中评估了这些类别中有病和无病婴儿的比例,结果显示出相似的模式。生长较慢和较快均与支气管肺发育不良相关,而只有生长较慢与早产儿视网膜病变相关。
本研究使用2023年早产儿产后生长图表,提出了一种体重增长分类的替代方法。