Liu Na, Yang Xiao, Guo Dongyan, Wang Qi, Zhang Jianhua, Wang Xiaoming
Relevant Departments For Infection Control, Jinan Mingshui Eye Hospital, Longquan Road 5601, Zhangqiu District, Jinan, China.
Cataract Department, Jinan Mingshui Eye Hospital, Longquan Road 5601, Zhangqiu District, Jinan, China.
BMC Ophthalmol. 2025 Aug 12;25(1):455. doi: 10.1186/s12886-025-04291-6.
The goals of this study was to analyze and explore the effect of comprehensive sensory control strategy on prevention and control of infectious endophthalmitis after cataract surgery.
From January 2012 to December 2023, a study of patients with infectious endophthalmitis after cataract surgery was conducted in a hospital. Perioperative infection prevention measures include topical eye drops, lacrimal irrigation, povidone iodine disinfection of conjunctival sac, etc. After in-depth investigation and analysis of the reasons for the increase in the incidence of endophthalmitis for three times, a series of effective prevention and control measures were proposed for the root causes of the problems, including optimizing the key link system, implementing closed-loop management of sensory control measures, designing personalized children's surgery plan, strengthening perioperative treatment, comprehensively monitoring the operating room clean system, strengthening the cleaning and disinfection treatment between consecutive operations to ensure the safety of the operating environment, etc. RESULTS: From January 2012 to December 2023, a total of 134,045 cataract operations were performed, of which 26 cases were infected at the surgical site, with an infection rate of 0.019%. According to the specific infection characteristics of each period, corresponding prevention and control measures were formulated and implemented, which significantly reduced the incidence of endophthalmitis (P < 0.01). In 2012, 2016 and 2020, the incidence of endophthalmitis was 0.057%, 0.048% and 0.029%, respectively, showing a linear decreasing trend, which was statistically significant (X = 19.793, P ≤ 0.01).
By analyzing the characteristics of infectious endophthalmitis in different periods, the main causes can be inferred, and the prevention and control measures can be explored to effectively reduce the incidence of infectious endophthalmitis after cataract surgery.
本研究旨在分析和探讨综合感控策略对白内障手术后感染性眼内炎防控的效果。
2012年1月至2023年12月，某医院对白内障手术后发生感染性眼内炎的患者进行研究。围手术期感染预防措施包括局部滴眼、泪道冲洗、结膜囊聚维酮碘消毒等。在三次深入调查分析眼内炎发病率上升原因后，针对问题根源提出了一系列有效的防控措施，包括优化关键环节制度、实施感控措施闭环管理、设计个性化儿童手术方案、加强围手术期治疗、全面监测手术室清洁系统、加强连续手术间的清洁消毒处理以确保手术环境安全等。
2012年1月至2023年12月，共进行白内障手术134045例，其中手术部位感染26例，感染率为0.019%。根据各时期具体感染特点制定并实施相应防控措施，显著降低了眼内炎发病率（P<0.01）。2012年、2016年和2020年眼内炎发病率分别为0.057%、0.048%和0.029%，呈线性下降趋势，差异有统计学意义（X=19.793，P≤0.01）。
通过分析不同时期感染性眼内炎的特点，可推断主要病因，并探索防控措施，有效降低白内障手术后感染性眼内炎的发病率。
