Guo Chen, An Lifeng, Lu Geling, Huang Jingwen
Graduate School, Heilongjiang University of Chinese Medicine, Harbin, China.
Department of Basic Chinese Medicine, Jiamusi Campus of Heilongjiang University of Chinese Medicine, Jiamusi, China.
Medicine (Baltimore). 2025 Aug 8;104(32):e43802. doi: 10.1097/MD.0000000000043802.
Benign prostatic hyperplasia (BPH) affects >50% of males aged ≥50 years, causing lower urinary tract symptoms that significantly impair quality of life. While acupuncture is increasingly used for BPH management, its acupoint selection patterns remain unstandardized.
Clinical studies on acupuncture/moxibustion for BPH published before September 30, 2024, were retrieved from CNKI, WANFANG, VIP, PubMed, and ScienceDirect. Acupoint patterns were analyzed using the Traditional Chinese Medicine Inheritance Assistance Platform (TCMISS).
Among 270 articles, 85 met the inclusion criteria. Sixty-one acupoints were identified, with high-frequency selections including Guanyuan (CV4), Zhongji (CV3), Sanyinjiao (SP6), Qihai (CV6), Shenshu (BL23), Shuidao (ST28), Pangguangshu (BL28), Yinlingquan (SP9), Qugu (CV2), and Ciliao (BL32). The Conception Vessel (CV), Bladder (BL), and Spleen (SP) meridians were predominantly used, primarily distributed in the chest/abdomen (EX-CA) and back/waist (EX-BW) regions. Association rule analysis revealed strong correlations among acupoints, with key combinations being Zhongji (CV3)-Sanyinjiao (SP6), Guanyuan (CV4)-Qihai (CV6), and Guanyuan (CV4)-Sanyinjiao (SP6). Core therapeutic clusters centered on Zhongji (CV3), Guanyuan (CV4), and Shenshu (BL23), integrated with Sanyinjiao (SP6), Shuidao (ST28), and Yinlingquan (SP9).
Acupuncture for BPH primarily targets CV4, CV3, SP6, CV6, BL23, ST28, BL28, SP9, CV2, and BL32, reflecting their strong therapeutic relevance. These findings highlight meridians and acupoints potentially critical for symptom alleviation. However, rigorous clinical trials are warranted to validate efficacy and optimize protocols. This review provides a foundation for advancing evidence-based acupuncture interventions in BPH management.
良性前列腺增生(BPH)影响超过50%的50岁及以上男性,导致下尿路症状,严重损害生活质量。虽然针灸越来越多地用于BPH的治疗,但其穴位选择模式仍未标准化。
检索2024年9月30日前发表的关于针灸治疗BPH的临床研究,检索数据库包括中国知网、万方、维普、PubMed和ScienceDirect。使用中医传承辅助平台(TCMISS)分析穴位模式。
在270篇文章中,85篇符合纳入标准。共确定了61个穴位,高频选择包括关元(CV4)、中极(CV3)、三阴交(SP6)、气海(CV6)、肾俞(BL23)、水道(ST28)、膀胱俞(BL28)、阴陵泉(SP9)、曲骨(CV2)和次髎(BL32)。任脉(CV)、膀胱经(BL)和脾经(SP)使用较多,主要分布在胸腹部(EX-CA)和腰背部(EX-BW)区域。关联规则分析显示穴位之间存在强相关性,关键组合为中极(CV3)-三阴交(SP6)、关元(CV4)-气海(CV6)和关元(CV4)-三阴交(SP6)。核心治疗组方以中极(CV3)、关元(CV4)和肾俞(BL23)为中心,结合三阴交(SP6)、水道(ST28)和阴陵泉(SP9)。
针灸治疗BPH主要针对CV4、CV3、SP6、CV6、BL23、ST28、BL28、SP9、CV2和BL32,反映了它们较强的治疗相关性。这些发现突出了对缓解症状可能至关重要的经络和穴位。然而,需要严格的临床试验来验证疗效并优化方案。本综述为推进BPH管理中基于证据的针灸干预提供了基础。