Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, 211198, Nanjing, Jiangsu, China.
Center for New Drug Safety Evaluation and Research, China Pharmaceutical University, 211198, Nanjing, Jiangsu, China.
Wien Klin Wochenschr. 2021 Feb;133(3-4):153-162. doi: 10.1007/s00508-020-01692-z. Epub 2020 Jun 12.
Benign prostatic hyperplasia (BPH) is a common disease that can cause uncomfortable lower urinary tract symptoms. The occurrence of symptomatic BPH develops after the age of 40 years and increases gradually with age to reach more than 50% at the age of 60 years and severely disturbs the quality of life of the patients. Alpha-blockers and 5‑alpha reductase inhibitors are first-line agents used for the treatment of BPH. Due to the adverse effects of these conventional therapies, many patients turn to phytotherapy and other alternative therapies. This review covers alternative therapies, i.e., phytotherapy (cernilton, eviprostat, quercetin, saw palmetto and pumpkin seed) and physical therapy (acupuncture, aquablation, pulsed electromagnetic field, prostate urethral lift, radial extracorporeal shock wave therapy, thermobalancing therapy, and transurethral needle ablation) commonly used in the management of BPH.
良性前列腺增生症(BPH)是一种常见疾病,可引起不适的下尿路症状。有症状的 BPH 发生于 40 岁以后,且随年龄逐渐增加,60 岁时超过 50%,严重影响患者的生活质量。α受体阻滞剂和 5α还原酶抑制剂是 BPH 的一线治疗药物。由于这些常规治疗方法的不良反应,许多患者转而采用植物疗法和其他替代疗法。本文综述了 BPH 的常用替代疗法,即植物疗法(锯棕榈、南瓜籽油、荨麻叶、槲皮素、西力士)和物理疗法(针灸、水消融、脉冲电磁场、前列腺尿道松解术、径向体外冲击波治疗、热平衡治疗、经尿道针消融术)。