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基于三光束干涉仪的光纤尖端传感器,用于同时测量流速和温度。

Fiber-tip optic sensor based on a three-beam interferometer for simultaneous measurement of flow rate and temperature.

作者信息

Li Wenxue, Li Jinjian, Ye Jingfu, Xu Weijiang, Liu Yi, Qu Shiliang

出版信息

Opt Express. 2025 Mar 24;33(6):12509-12518. doi: 10.1364/OE.546828.

Abstract

Precise monitoring of the microfluidic flow rate is a key factor in microfluidic chips. However, the temperature of the microfluidics often affects the measuring results of the optical flow rate sensor. Here, we present a fiber-tip optical sensor based on a three-beam interferometer that can measure microfluidic flow rate and temperature simultaneously. The optical fiber sensor is composed of UV adhesive at the bottom of the microcavity sealed by liquid paraffin, and a section of air is reserved in the hollow core fiber (HCF). The flow of microfluidics will affect the pressure of the air cavity formed by UV adhesive and the paraffin. Microfluidics with different flow rates in the channel of the microfluidic chip have different effects on the position of the liquid paraffin in the cavity. Because of the small viscous force between the paraffin and the inner wall of the HCF, the length of the air cavity changed greatly as the flow rate changed resulting in a high flow rate sensitivity. The UV adhesive as a temperature measuring part has a high thermo-optical coefficient (TOC), as a temperature measuring part, utilized to measure the temperature of the microfluidics. The length variation of air cavity and refractive index (RI) of UV adhesive will cause the shifting of the dips in the interference spectrum. The rate sensitivity can reach -22.51 nm/(mm/s) in the range of 0.17 mm/s to 1.17 mm/s. In addition, the sensor has a stable temperature sensitivity of 13.513 nm/℃. This work provides a low-cost sensing platform for measuring various physical parameters in microfluidic chips, which is of great significance for on-chip biochemical reactions.

摘要

精确监测微流体流速是微流控芯片中的关键因素。然而,微流体的温度常常会影响光学流速传感器的测量结果。在此,我们展示了一种基于三光束干涉仪的光纤尖端光学传感器,它能够同时测量微流体流速和温度。该光纤传感器由底部用液体石蜡密封的微腔中的紫外胶组成,并且在空心光纤(HCF)中保留一段空气。微流体的流动会影响由紫外胶和石蜡形成的气腔的压力。微流控芯片通道中不同流速的微流体对腔内液体石蜡的位置有不同影响。由于石蜡与HCF内壁之间的粘性力较小,随着流速变化,气腔长度变化很大,从而导致高流速灵敏度。作为温度测量部件的紫外胶具有较高的热光系数(TOC),用于测量微流体的温度。气腔长度变化和紫外胶的折射率(RI)变化会导致干涉光谱中凹陷处的移动。在0.17 mm/s至1.17 mm/s范围内,流速灵敏度可达-22.51 nm/(mm/s)。此外,该传感器具有13.513 nm/℃的稳定温度灵敏度。这项工作为测量微流控芯片中的各种物理参数提供了一个低成本的传感平台,这对芯片上的生化反应具有重要意义。

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