Model Design and Study of a U-Channel Photonic Crystal Fib Optic Sensor for Measuring Glucose Concentration in Blood.

This research introduces a biosensor utilizing surface plasmon resonance in a photonic crystal fiber (PCF) configuration. PCF uses fused silica as the base material, with a layer of gold placed over the U-channels in the cross-section of the fiber to create a surface plasmon resonance. There are three different sizes of internal fiber optic air hole diameters, with a larger channel circle below the u-channel for the formation of an energy leakage window. COMSOL software 6.0 assisted us in tuning the fiber optic structure and performance for the study, and the structural parameters analyzed mainly include the channel circle diameter, the channel circle spacing, the profundity measurement of the polished layer, and the nanoscale size variation of metal films. The results of the simulation study show that the optical fiber sensor achieves refractive index (RI) responsiveness across the 1.30 to 1.41 range, and in the RI interval of 1.40 to 1.41, the sensor exhibits the largest resonance peak shift, and its highest sensitivity reaches 10,200 nm/RIU, and the smallest full width at half peak (FWHM) corresponds to the RI of 1.34 with a value of 4.8 nm, and the highest figure of merit (FOM) corresponds to the RI of 1.34 with a value of 895.83 (1/RIU). COMSOL 6.0 simulation software, was used to simulate the changes in blood refractive index corresponding to different glucose concentrations, and the detection performance of the sensor for different concentrations of glucose was tested. Then, the results show that the glucose concentration in 75 mg/dL-175 mg/dL with RI detection sensitivity is 3750 nm/RIU, where the maximum refractive index sensitivity is 5455 nm/RIU. It shows that the sensor can be applied in the field of biomedical applications, with its convenience, fast response, and high sensitivity, it has great potential and development prospect in the market.