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用于早期卵巢癌检测的电化学生物传感器的综合分析

Comprehensive analysis of electrochemical biosensors for early ovarian cancer detection.

作者信息

El-Gammal Marwa A, Sayed Fatma E, Allam Nageh K

机构信息

Energy Materials Laboratory, Physics Department, School of Sciences and Enginnering, The American University in Cairo New Cairo 11835 Egypt

Biotechnology program, Faculty of Agriculture, Ain Shams University Cairo 11566 Egypt.

出版信息

RSC Adv. 2024 Nov 25;14(50):37580-37597. doi: 10.1039/d4ra05972g. eCollection 2024 Nov 19.

Abstract

Ovarian cancer is one of the leading causes of mortality among women worldwide. However, early detection can significantly reduce mortality rates and mitigate subsequent complications related to both economic burden and mental well-being. Despite the development in the field of medical diagnosis, the death rates due to ovarian cancer have sharply increased. Among the recent technologies suggested as suitable diagnostic techniques for the early detection of ovarian cancer, biosensor technology has emerged as a cutting-edge technology, with electrochemical biosensors providing one of the most efficient types of biosensors. Therefore, this review discusses the application of electrochemical biosensors as a viable alternative to conventional diagnostic techniques for the timely identification of ovarian cancer, its advantages over other types of biosensors and conventional diagnostic techniques, and the types of electrochemical biosensors.

摘要

卵巢癌是全球女性死亡的主要原因之一。然而,早期检测可显著降低死亡率,并减轻与经济负担和心理健康相关的后续并发症。尽管医学诊断领域有所发展,但卵巢癌导致的死亡率却急剧上升。在最近被建议作为卵巢癌早期检测适用诊断技术的技术中,生物传感器技术已成为一项前沿技术,其中电化学生物传感器是最有效的生物传感器类型之一。因此,本综述讨论了电化学生物传感器作为传统诊断技术的可行替代方案在及时识别卵巢癌方面的应用、其相对于其他类型生物传感器和传统诊断技术的优势,以及电化学生物传感器的类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7072/11587864/85c6460e712e/d4ra05972g-f1.jpg

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