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Modeling lymph node metastases in vivo.

作者信息

Gonzalez Rodrigo J, Peng Changwei, von Andrian Ulrich H

机构信息

Department of Immunology, Harvard Medical School, Boston, MA, USA.

The Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.

出版信息

Nat Protoc. 2025 Aug 13. doi: 10.1038/s41596-025-01235-8.

DOI:10.1038/s41596-025-01235-8
PMID:40804177
Abstract
摘要

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本文引用的文献

1
Lymph node colonization induces tumor-immune tolerance to promote distant metastasis.淋巴结定植诱导肿瘤免疫耐受以促进远处转移。
Cell. 2022 May 26;185(11):1924-1942.e23. doi: 10.1016/j.cell.2022.04.019. Epub 2022 May 6.
2
Lymph nodes-The neglected battlefield in tuberculosis.淋巴结——结核病被忽视的战场。
PLoS Pathog. 2020 Aug 13;16(8):e1008632. doi: 10.1371/journal.ppat.1008632. eCollection 2020 Aug.
3
Subsets of exhausted CD8 T cells differentially mediate tumor control and respond to checkpoint blockade.耗竭的 CD8 T 细胞亚群差异介导肿瘤控制并对检查点阻断产生反应。
Nat Immunol. 2019 Mar;20(3):326-336. doi: 10.1038/s41590-019-0312-6. Epub 2019 Feb 18.
4
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice.在小鼠中，淋巴结转移灶可侵犯局部血管，离开淋巴结，并在远处器官形成转移灶。
Science. 2018 Mar 23;359(6382):1403-1407. doi: 10.1126/science.aal3622. Epub 2018 Mar 22.
5
Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma.黑色素瘤前哨淋巴结转移的完全解剖或观察
N Engl J Med. 2017 Jun 8;376(23):2211-2222. doi: 10.1056/NEJMoa1613210.
6
Systemic Immunity Is Required for Effective Cancer Immunotherapy.有效的癌症免疫疗法需要全身免疫。
Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19.
7
A perspective on cancer cell metastasis.癌症细胞转移的观点。
Science. 2011 Mar 25;331(6024):1559-64. doi: 10.1126/science.1203543.