Santoro Emanuela, Russo Michela, Manente Roberta, Schettino Valentina, Moccia Giuseppina, Andretta Vincenzo, Cerrone Valentina, Capunzo Mario, Boccia Giovanni
Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Salerno, Italy.
Clinical Pathology Unit, San Giovanni di Dio e Ruggi d'Aragona University Hospital, 84081 Salerno, Italy.
Healthcare (Basel). 2025 Jul 23;13(15):1790. doi: 10.3390/healthcare13151790.
: Hospitals are environments where care-related infections (HAIs) can occur, including those caused by resistant microorganisms. In addition, inappropriate use of antibiotics contributes to the development of antimicrobial resistance (AMR), a serious public health challenge. As part of the "Choosing Wisely-Italy" initiative, this study complements a previous publication on hand hygiene compliance in an intensive care unit (ICU) by analyzing antibiotic consumption over the same period and comparing it with the previous two years. : A nine-month observational study was carried out from January to September 2018 in the ICU of a university hospital in Salerno province. Antibiotic order forms from the observation period were compared with those from the same months in 2016 and 2017. Glove consumption and costs were also analyzed over the three-year period. Statistical analysis was performed using ORIGIN* and EXCEL* software. : Overall antibiotic consumption during the observational period aligned with national averages reported in the National Plan to Combat Antimicrobial Resistance (PNCAR). : These findings suggest that the presence of regular external monitoring may positively influence antibiotic use and hygiene behavior. Further research is needed to assess the long-term impact of observational interventions on clinical practice and AMR containment.
医院是可能发生与护理相关感染（医院获得性感染，HAIs）的环境，包括由耐药微生物引起的感染。此外，抗生素的不当使用会导致抗菌药物耐药性（AMR）的产生，这是一个严峻的公共卫生挑战。作为“明智选择 - 意大利”倡议的一部分，本研究通过分析同一时期的抗生素使用情况并与前两年进行比较，对之前一篇关于重症监护病房（ICU）手卫生依从性的出版物进行了补充。
2018年1月至9月，在萨勒诺省一家大学医院的ICU进行了一项为期九个月的观察性研究。将观察期内的抗生素订单与2016年和2017年同月的订单进行比较。还分析了三年期间手套的消耗量和成本。使用ORIGIN和EXCEL软件进行统计分析。
观察期内的总体抗生素使用情况与《国家抗菌药物耐药性防治计划》（PNCAR）中报告的全国平均水平一致。
这些发现表明，定期外部监测的存在可能会对抗生素使用和卫生行为产生积极影响。需要进一步研究以评估观察性干预措施对临床实践和抗菌药物耐药性控制的长期影响。
