Ingallina Cinzia, Spano Mattia, Prencipe Sabrina Antonia, Vinci Giuliana, Di Sotto Antonella, Ambroselli Donatella, Vergine Valeria, Crestoni Maria Elisa, Di Meo Chiara, Zoratto Nicole, Izzo Luana, Navarré Abel, Adiletta Giuseppina, Russo Paola, Di Matteo Giacomo, Mannina Luisa, Giusti Anna Maria
Department of Chemistry and Technology of Drugs, Sapienza University of Rome, 00185 Rome, Italy.
Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy.
Nutrients. 2025 Jul 31;17(15):2528. doi: 10.3390/nu17152528.
In light of pressing global nutritional needs, the valorization of agri-food waste constitutes a vital strategy for enhancing human health and nutrition, while simultaneously supporting planetary health. This integrated approach is increasingly indispensable within sustainable and equitable food systems. Recently, a sustainability-driven focus has shifted attention toward the valorization of the agri-food by-products as rich sources of bioactive compounds useful in preventing or treating chronic diseases. Agri-food by-products, often regarded as waste, actually hold great potential as they are rich in bioactive components, dietary fiber, and other beneficial nutrients from which innovative food ingredients, functional foods, and even therapeutic products are developed. This review aims to provide a comprehensive analysis of the current advances in recovering and applying such compounds from agri-food waste, with a particular focus on their roles in human health, sustainable packaging, and circular economy strategies. : This review critically synthesizes recent scientific literature on the extraction, characterization, and utilization of bioactive molecules from agri-food by-products. After careful analysis of the PubMed and Scopus databases, only English-language articles from the last 10 years were included in the final narrative review. The analysis also encompasses applications in the nutraceutical, pharmaceutical, and food packaging sectors. : Emerging technologies have enabled the efficient and eco-friendly recovery of compounds such as polyphenols, carotenoids, and dietary fibers that demonstrate antioxidant, antimicrobial, and anti-inflammatory properties. These bioactive compounds support the development of functional foods and biodegradable packaging materials. Furthermore, these valorization strategies align with global health trends by promoting dietary supplements that counteract the effects of the Western diet and chronic diseases. : Valorization of agri-food by-products offers a promising path toward sustainable development by reducing waste, enhancing public health, and driving innovation. This strategy not only minimizes waste and supports sustainability, but also promotes a more nutritious and resilient food system.
鉴于全球紧迫的营养需求，农业食品废弃物的增值利用是增进人类健康与营养、同时支持地球健康的一项重要战略。在可持续且公平的食品系统中，这种综合方法愈发不可或缺。近来，受可持续发展驱动，人们的关注点已转向将农业食品副产品作为预防或治疗慢性病的生物活性化合物的丰富来源进行增值利用。农业食品副产品通常被视为废弃物，实际上却具有巨大潜力，因为它们富含生物活性成分、膳食纤维和其他有益营养素，可从中开发创新型食品配料、功能性食品乃至治疗性产品。本综述旨在全面分析从农业食品废弃物中回收和应用此类化合物的当前进展，尤其关注它们在人类健康、可持续包装及循环经济战略中的作用。：本综述批判性地综合了近期关于从农业食品副产品中提取、表征和利用生物活性分子的科学文献。在仔细分析PubMed和Scopus数据库后，最终的叙述性综述仅纳入了过去10年的英文文章。分析还涵盖了在营养保健品、制药和食品包装领域的应用。：新兴技术已实现高效且环保地回收具有抗氧化、抗菌和抗炎特性的多酚、类胡萝卜素和膳食纤维等化合物。这些生物活性化合物有助于开发功能性食品和可生物降解包装材料。此外，这些增值利用策略通过推广抵消西方饮食和慢性病影响的膳食补充剂，与全球健康趋势保持一致。：农业食品副产品的增值利用通过减少废弃物、增进公众健康和推动创新，为可持续发展提供了一条充满希望的道路。这一战略不仅能最大限度减少废弃物并支持可持续性，还能促进建立更具营养且更具韧性的食品系统。
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