Alzahrani Hanadi G, AlSarhan Mohammed A, Aldohayan Abdullah, Bamehriz Fahad, Alzoman Hamad A
Graduate Program in Periodontics, Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Saudi Dent J. 2024 Jun;36(6):940-946. doi: 10.1016/j.sdentj.2024.04.005. Epub 2024 Apr 18.
The association between sleeve gastrectomy and halitosis remains relatively unknown. Therefore, this study aimed to evaluate the effect of sleeve gastrectomy on halitosis and the oral bacterial species associated with halitosis in patients with obesity.
This was a prospective longitudinal cohort study that examined patients before and after sleeve gastrectomy and followed the patients at three time intervals (1, 3, and 6 months) after sleeve gastrectomy. Clinical periodontal measurements (plaque index [PI], gingival index [GI], and probing depth [PD]) were obtained. In addition, plaque samples were collected for quantification of the periodontopathogenic bacteria: Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Fusobacterium nucleatum using real-time quantitative polymerase chain reaction (qPCR). In addition, breath samples were collected to analyze the concentration of volatile sulfur compounds (VSCs), namely hydrogen sulfide (H2S), methyl mercaptan (CH3SH), and dimethyl sulfide (CH3SCH3), via portable gas chromatography (Oral Chroma™).
Of the 43 patients initially included, 39 completed the study, with a mean age of 32.2 ± 10.4 years. For PI and GI repeated measurements one way analysis of variance showed a significant increase (p-value < 0.001 for both) one month after surgery, with mean values of 1.3 and 1.59, respectively, compared to the baseline. During the same period, the number of increased, with a p-value = 0.04. Similarly, the levels of hydrogen sulfide (H2S) and methyl mercaptan (CH3SH) increased significantly in the first month after surgery (p-value = 0.02 and 0.01, respectively).
This study demonstrated that sleeve gastrectomy may lead to increased halitosis one month post-surgery, attributed to elevated and counts, contributing to the development of gingivitis in obese patients who underwent sleeve gastrectomy. This emphasizes the importance of including oral health professionals in the multidisciplinary team for the management of patients undergoing bariatric surgery.
袖状胃切除术与口臭之间的关联仍相对不为人知。因此，本研究旨在评估袖状胃切除术对肥胖患者口臭及与口臭相关的口腔细菌种类的影响。
这是一项前瞻性纵向队列研究，对袖状胃切除术前后的患者进行检查，并在袖状胃切除术后的三个时间点（1、3和6个月）对患者进行随访。获取临床牙周测量指标（菌斑指数[PI]、牙龈指数[GI]和探诊深度[PD]）。此外，收集菌斑样本，使用实时定量聚合酶链反应（qPCR）对牙周病原菌进行定量：牙龈卟啉单胞菌、福赛坦纳菌、具核梭杆菌和齿垢密螺旋体。另外，收集呼气样本，通过便携式气相色谱仪（Oral Chroma™）分析挥发性硫化物（VSCs）的浓度，即硫化氢（H2S）、甲硫醇（CH3SH）和二甲基硫醚（CH3SCH3）。
最初纳入的43例患者中，39例完成了研究，平均年龄为32.2±10.4岁。对于PI和GI的重复测量，单因素方差分析显示术后1个月有显著增加（两者p值均<0.001），与基线相比，平均值分别为1.3和1.59。在同一时期，数量增加，p值=0.04。同样，术后第1个月硫化氢（H2S）和甲硫醇（CH3SH）水平显著升高（p值分别为0.02和0.01）。
本研究表明，袖状胃切除术可能在术后1个月导致口臭增加，这归因于数量增加，导致接受袖状胃切除术的肥胖患者发生牙龈炎。这强调了在多学科团队中纳入口腔健康专业人员对肥胖手术患者进行管理的重要性。
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