Mohseni Ghalehghazi Amin, Zhong Wen
Department of Biosystems Engineering, University of Manitoba, Winnipeg, MB R3P 0W8, Canada.
Molecules. 2025 Aug 4;30(15):3260. doi: 10.3390/molecules30153260.
Valued for their nutritional content, eggs have recently gained attention as a versatile biomaterial owing to their biocompatibility, biodegradability, and unique structural and biochemical composition. This review highlights the biomedical potential of various egg components-eggshell, eggshell membrane, egg white, and egg yolk-and their applications in bone grafting, tissue engineering, wound healing, drug delivery, and biosensors. Eggshells serve as a natural, calcium-rich source for bone tissue engineering and regenerative medicine. The eggshell membrane, with its antimicrobial and structural properties, offers promise as a wound healing scaffold. Egg white, known for its gelation and film-forming capabilities, is utilized in hydrogel-based systems for drug delivery and biosensing. Egg yolk, rich in lipids and immunoglobulin Y (IgY) antibodies, is being explored for diagnostic and therapeutic applications. This review critically examines the advantages and limitations of each egg-derived component and outlines current research gaps, offering insights into future directions for the development of egg-based biomaterials in biomedical engineering.
鸡蛋因其营养成分而备受重视,最近作为一种多功能生物材料受到关注,这是由于其生物相容性、生物降解性以及独特的结构和生化组成。本综述重点介绍了各种鸡蛋成分——蛋壳、蛋壳膜、蛋清和蛋黄——的生物医学潜力及其在骨移植、组织工程、伤口愈合、药物递送和生物传感器中的应用。蛋壳作为骨组织工程和再生医学中天然的、富含钙的来源。蛋壳膜具有抗菌和结构特性,有望作为伤口愈合支架。蛋清以其凝胶化和成膜能力而闻名,被用于基于水凝胶的药物递送和生物传感系统。蛋黄富含脂质和免疫球蛋白Y(IgY)抗体,正在探索其诊断和治疗应用。本综述批判性地研究了每种鸡蛋衍生成分的优点和局限性,并概述了当前的研究空白,为生物医学工程中基于鸡蛋的生物材料的未来发展方向提供了见解。