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基于细菌纤维素的导管的物理机械性能及透氧性研究

Study of the Physico-Mechanical Properties and Oxygen Permeability of Bacterial-Cellulose-Based Conduits.

作者信息

Parchaykina Marina V, Baykov Mikhail A, Revina Elvira S, Shchankin Mikhail V, Revin Viktor V

机构信息

Department of Biotechnology and Biochemistry, National Research Ogarev Mordovia State University, 430005 Saransk, Russia.

出版信息

Polymers (Basel). 2025 Jul 31;17(15):2123. doi: 10.3390/polym17152123.

Abstract

The article is devoted to the study of the physico-mechanical properties and oxygen permeability of the examined conduits based on bacterial cellulose (BC) obtained using the B-11267 strain. BC is considered a promising material for regenerative biomedicine. The chemical structure, crystallinity degree and porosity of BC-based conduits were characterized by means of infrared spectroscopy (IR-spectroscopy), scanning electron microscopy (SEM) and atomic-force microscopy (AFM). Both the Young's modulus and determined tension showed the high strength of the obtained conduits. Their oxygen permeability exceeded the values for the existing analogues, and lack of cytotoxicity indicated biocompatibility, confirming that BC-based conduits may be used for biomedical purposes.

摘要

本文致力于研究基于使用B - 11267菌株获得的细菌纤维素(BC)的受试导管的物理机械性能和透氧性。BC被认为是再生生物医学的一种有前景的材料。通过红外光谱(IR光谱)、扫描电子显微镜(SEM)和原子力显微镜(AFM)对基于BC的导管的化学结构、结晶度和孔隙率进行了表征。所得导管的杨氏模量和测定的张力均显示出高强度。它们的透氧性超过了现有类似物的值,并且缺乏细胞毒性表明具有生物相容性,这证实了基于BC的导管可用于生物医学目的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2089/12349113/42d80d1b9c68/polymers-17-02123-g001.jpg

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