Winn P, Herberg L J
Physiol Behav. 1985 Nov;35(5):683-7. doi: 10.1016/0031-9384(85)90397-x.
Male rats fed on a varied, palatable supermarket diet for 11 weeks gained more weight than chow-fed controls. When palatable food was discontinued, their body weights became static, but remained significantly higher than control weights for a further 5 weeks. Hoarding of food was readily elicited by food deprivation in the dietarily obese as well as in the chow-fed rats. Previous studies have shown that the critical body weight at which hoarding appears does not covary with body weight, but appears to reflect a defended level of body weight. In the present study, critical weights were not significantly different between groups before supermarket diet, but were significantly higher in the supermarket rats after obesity had developed. Thus, the increase in body weight brought about by a supermarket diet (unlike that in ventromedial hypothalamic obesity) can be accompanied by an increase in the defended level of body weight as inferred from the critical weight for the onset of hoarding behaviour.
以多样化、美味的超市食品喂养11周的雄性大鼠比喂食普通饲料的对照组体重增加更多。当停止提供美味食物时,它们的体重不再增加,但在接下来的5周内仍显著高于对照组体重。饮食性肥胖大鼠以及喂食普通饲料的大鼠在食物匮乏时都很容易出现食物囤积行为。先前的研究表明,出现食物囤积行为的临界体重与体重并不相关,而是似乎反映了一个受保护的体重水平。在本研究中,在开始食用超市食品之前,两组的临界体重没有显著差异,但在肥胖形成后,食用超市食品的大鼠的临界体重显著更高。因此,由超市食品饮食导致的体重增加(与腹内侧下丘脑性肥胖不同)可能伴随着从食物囤积行为开始的临界体重推断出的受保护体重水平的增加。