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[关注声明] ETS-1:通过调节胰腺癌中的葡萄糖代谢成为代谢治疗的潜在糖酵解靶点。

[Expression of Concern]  ETS‑1: A potential target of glycolysis for metabolic therapy by regulating glucose metabolism in pancreatic cancer.

作者信息

Zhang Xiu, Wu Dan, Aldarouish Mohanad, Yin Xiaodong, Li Chunyan, Wang Cailian

机构信息

Department of Oncology, Zhongda Hospital, Medical School of Southeast University, Nanjing, Jiangsu 210009, P.R. China.

Department of Oncology, Jiangyin People's Hospital, Jiangyin, Jiangsu 224000, P.R. China.

出版信息

Int J Oncol. 2025 Oct;67(4). doi: 10.3892/ijo.2025.5786. Epub 2025 Aug 14.

Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that, regarding the western blots shown in Figs. 4B and 5B, the AMPK panel in Fig. 4B looked strikingly similar to the ATG5 panel in Fig. 5B, and the p‑AMPK panel in Fig. 4B looked highly similar to the ATG7 panel in Fig. 5B. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper, although up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office conitnues to investigate this matter further. [International Journal of Oncology 50: 232-240, 2017; DOI: 10.3892/ijo.2016.3770].

摘要

上述论文发表后,一位关注此事的读者提醒编辑注意,关于图4B和图5B所示的蛋白质印迹,图4B中的AMPK条带与图5B中的ATG5条带惊人地相似,图4B中的p-AMPK条带与图5B中的ATG7条带高度相似。编辑部已与作者联系,要求他们对本文数据呈现中的这些明显异常作出解释,但截至目前,尚未收到他们的回复。鉴于编辑部已意识到围绕本文科学诚信的潜在问题,我们特此发布关注声明,在编辑部继续对此事进行进一步调查的同时,告知读者这一潜在问题。[《国际肿瘤学杂志》50: 232 - 240, 2017; DOI: 10.3892/ijo.2016.3770]

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