Vaccarino F J, Franklin K B, Prupas D
Physiol Behav. 1985 Nov;35(5):741-7. doi: 10.1016/0031-9384(85)90405-6.
The present study investigated the role of the superior colliculus (SC) in the expression of opposing locomotor asymmetries elicited from the medial and lateral substantia nigra pars compacta (SNC). In experiment one it was found that amphetamine stimulated ipsiversive circling produced by unilateral SC lesions was additive with the ipsiversive circling produced by alpha-flupenthixol microinjections into the lateral SNC but was not additive with the contraversive circling produced by such injections into the medial SNC. Experiment two showed that the amphetamine stimulated ipsiversive circling produced by unilateral SC lesions was additive with the contraversive circling produced by lateral SNC lesions but was not additive with the ipsiversive circling produced by medial SNC lesions. Both experiments were taken to suggest that the striato-nigral-colliculus system is an output path for medial SNC derived circling but is not an output path for the opposing circling behavior derived from the lateral SNC.
本研究调查了上丘（SC）在由内侧和外侧黑质致密部（SNC）引发的相反运动不对称表达中的作用。在实验一中发现，由单侧SC损伤产生的苯丙胺刺激的同侧旋转与向外侧SNC内微量注射α-氟哌噻吨产生的同侧旋转具有相加性，但与向内侧SNC内进行此类注射产生的对侧旋转不具有相加性。实验二表明，由单侧SC损伤产生的苯丙胺刺激的同侧旋转与外侧SNC损伤产生的对侧旋转具有相加性，但与内侧SNC损伤产生的同侧旋转不具有相加性。两个实验均表明，纹状体-黑质-上丘系统是内侧SNC衍生的旋转行为的输出路径，但不是外侧SNC衍生的相反旋转行为的输出路径。
