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腰骶神经根病患者的治疗选择与医疗服务利用情况:一项随机对照试验的结果

Treatment Choices and Healthcare Services Utilization Amongst Lumbosacral Radiculopathy Patients: Results from a Randomized Controlled Trial.

作者信息

Wexler Ryan S, Parman Natasha, Fox Devon J, ZuZero Danielle, Parikshak Anand, Kwin Sophia, Thompson Austin R, Carlson Hans L, Kern Thomas, Mist Scott D, Bradley Ryan, Zwickey Heather, Pickworth Courtney K

机构信息

Helfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.

Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA.

出版信息

OBM Integr Compliment Med. 2025;10(3). doi: 10.21926/obm.icm.2503035. Epub 2025 Aug 7.

Abstract

Lumbosacral radicular pain (LRP) is a common sequelae of low back pain, the world's leading cause of years lived with disability. LRP typically causes numbness, weakness, and tingling into the lower extremity and is associated with high rates of pain and impaired function. Despite its prevalence, there is significant heterogeneity among clinical practice guidelines for the treatment of LRP, which may contribute to poor patient outcomes. The aim of the present study was to identify treatments that participants had previously attempted before enrolling in a randomized controlled trial of a mindfulness-based intervention. This analysis evaluated prior pharmaceutical use, procedures, and non-pharmacologic treatments, with a special focus on complementary and integrative health (CIH) utilization. The data for the present analysis were taken from the health history form of the baseline visit for the randomized controlled trial by Wexler et al 2024. Treatment utilization was evaluated and reported using descriptive characteristics. In this sample of chronic LRP patients ( = 71), we found a high proportion of CIH utilization, including acupuncture (58%), chiropractic care (58%), and herbs/supplements (42%). Most patients (52%) were utilizing two or more CIH modalities to manage their pain. A high percentage of participants had also previously used non-steroidal anti-inflammatories (61%) to manage their pain, and over a third of participants had previously undergone an epidural steroid injection (34%). In our trial, CIH utilization was much higher for treatments like chiropractic care, acupuncture, natural products, and physical activity than has been reported in previous large datasets of patients with chronic pain such as the National Health Interview Survey. Collecting data on CIH utilization in clinical trials can enable researchers to compare their samples to large national datasets and identify differences in use among specific populations. In addition, healthcare utilization data collected in clinical trials can further inform the development of clinical practice guidelines.

摘要

腰骶神经根性疼痛(LRP)是腰痛的常见后遗症,而腰痛是全球导致残疾年数的首要原因。LRP通常会导致下肢麻木、无力和刺痛,并与高疼痛率和功能受损相关。尽管其患病率很高,但LRP治疗的临床实践指南之间存在显著异质性,这可能导致患者预后不佳。本研究的目的是确定参与者在参加一项基于正念干预的随机对照试验之前曾尝试过的治疗方法。该分析评估了先前的药物使用、治疗程序和非药物治疗,特别关注补充和综合健康(CIH)的利用情况。本分析的数据取自Wexler等人2024年随机对照试验基线访视的健康史表格。使用描述性特征对治疗利用情况进行评估和报告。在这个慢性LRP患者样本(n = 71)中,我们发现CIH利用比例很高,包括针灸(58%)、整脊治疗(58%)和草药/补充剂(42%)。大多数患者(52%)使用两种或更多的CIH方式来管理疼痛。很大比例的参与者之前也使用过非甾体抗炎药(61%)来控制疼痛,超过三分之一的参与者之前接受过硬膜外类固醇注射(34%)。在我们的试验中,整脊治疗、针灸、天然产品和体育活动等治疗方法的CIH利用率比之前慢性疼痛患者的大型数据集(如国家健康访谈调查)中报告的要高得多。在临床试验中收集CIH利用数据可以使研究人员将他们的样本与大型国家数据集进行比较,并确定特定人群之间使用情况的差异。此外,临床试验中收集的医疗保健利用数据可以进一步为临床实践指南的制定提供信息。

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本文引用的文献

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