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普通腺样牙源性肿瘤的滤泡外变异型:1例罕见病例报告

Extrafollicular Variant of the Common Adenomatoid Odontogenic Tumour: A Rare Case Report.

作者信息

Sangala Bhavani N, Buva Kirti, More Saudamini, Patil Amit, Akula Sandhya Rani, Sachdev Sanpreet S

机构信息

Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Mumbai, IND.

Public Health Dentistry, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Mumbai, IND.

出版信息

Cureus. 2025 Jul 13;17(7):e87846. doi: 10.7759/cureus.87846. eCollection 2025 Jul.

Abstract

Adenomatoid odontogenic tumour (AOT) is a benign epithelial neoplasm of odontogenic origin, typically seen in young female patients and commonly associated with impacted canines in the anterior maxilla. The extrafollicular variant, which is not associated with unerupted teeth, is relatively rare and may present diagnostic challenges due to its similarity with other odontogenic cysts or tumours. This report presents a case of a 23-year-old female patient with a gradually enlarging swelling in the anterior maxilla. Radiographic imaging revealed a well-defined radiolucency with root resorption and displacement of adjacent teeth. Histopathological examination confirmed the diagnosis of extrafollicular AOT. The lesion was managed successfully with conservative surgical excision, and no recurrence was noted during a two-year follow-up. This case highlights the importance of integrating clinical, radiological, and histopathological findings for accurate diagnosis and appropriate management of this rare AOT variant.

摘要

腺牙源性肿瘤(AOT)是一种牙源性良性上皮性肿瘤,多见于年轻女性患者,通常与上颌前部阻生尖牙有关。非滤泡型变异型与未萌出牙齿无关,相对罕见,因其与其他牙源性囊肿或肿瘤相似,可能带来诊断挑战。本报告介绍了一例23岁女性患者,上颌前部有逐渐增大的肿物。影像学检查显示边界清晰的透射区,伴有牙根吸收和邻牙移位。组织病理学检查确诊为非滤泡型AOT。通过保守性手术切除成功处理了该病变,在两年随访期间未发现复发。该病例强调了整合临床、放射学和组织病理学检查结果对于准确诊断和妥善处理这种罕见的AOT变异型的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af2d/12344608/e73eec5cbb61/cureus-0017-00000087846-i01.jpg

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