Siewiera Johan, Erlebacher Adrian
Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, 94143, USA.
Biomedical Sciences Program, University of California San Francisco, San Francisco, CA, 94143, USA.
Curr Opin Physiol. 2020 Feb;13:6-13. doi: 10.1016/j.cophys.2019.08.004. Epub 2019 Aug 27.
The myometrium, like all tissues, is home to a cadre of different kinds of leukocytes. As with other tissues, these leukocytes are presumed to contribute not only to host defense, but also to tissue remodeling and repair. The contributions of leukocytes to the specialized functions of the myometrium, however, remain almost unknown. Here, we provide an overview on this understudied aspect of myometrial physiology, with special emphasis on the potential role of myometrial leukocytes in pregnancy and parturition.
与所有组织一样,子宫肌层是多种不同类型白细胞的家园。与其他组织一样,这些白细胞不仅被认为有助于宿主防御,还参与组织重塑和修复。然而,白细胞对子宫肌层特殊功能的贡献几乎仍不为人所知。在此,我们概述子宫肌层生理学这一研究不足的方面,特别强调子宫肌层白细胞在妊娠和分娩中的潜在作用。