Shemali Yasmin, Khambaty Tasneem, Goodman Zachary, Ironson Gail
Department of Psychology, University of Miami, Miami, USA.
Department of Psychology, University of Maryland, Baltimore County, Baltimore, USA.
J Behav Med. 2025 Aug 14. doi: 10.1007/s10865-025-00588-5.
To investigate the link between HbA1c, a marker of glucose control, and positive emotional well-being (PEWB). Data were from a nationwide survey (N = 1933) which included an older, chronically ill subgroup (N = 905). Two aspects of PEWB were assessed via cross-sectional regression analyses predicting HbA1c from positive affect and life satisfaction individually, controlling for demographic variables. HbA1c was analyzed via blood-spot from a finger-prick. The mediating role of health behaviors (smoking, alcohol, BMI, and moderate exercise) were also examined. Higher positive affect and life satisfaction were significantly related to lower HbA1c in the overall and older, chronically ill samples controlling for demographics, as well as health behaviors and depression. Individuals with lower positive affect and lower life satisfaction were at increased odds of having clinically elevated HbA1c (> 6.5), indicative of diabetes, in both the overall sample (OR = 1.37; and OR = 1.13) and the chronically ill, older sample (OR = 1.59; and OR = 1.14). Two health behaviors emerged as mediators in the overall sample: BMI and exercise. These findings suggest that PEWB factors such as positive affect and life satisfaction are associated with HbA1c in both the general population and older, chronically ill individuals. Health factors such as BMI and moderate exercise mediate this relationship.
为了研究血糖控制指标糖化血红蛋白（HbA1c）与积极情绪幸福感（PEWB）之间的联系。数据来自一项全国性调查（N = 1933），其中包括一个老年慢性病亚组（N = 905）。通过横断面回归分析分别从积极情感和生活满意度预测HbA1c，并控制人口统计学变量，对PEWB的两个方面进行了评估。通过手指采血的血斑分析HbA1c。还研究了健康行为（吸烟、饮酒、体重指数和适度运动）的中介作用。在控制了人口统计学、健康行为和抑郁因素的总体样本以及老年慢性病样本中，较高的积极情感和生活满意度与较低的HbA1c显著相关。在总体样本（OR = 1.37；以及OR = 1.13）和慢性病老年样本（OR = 1.59；以及OR = 1.14）中，积极情感较低和生活满意度较低的个体临床HbA1c升高（> 6.5）即表明患有糖尿病的几率增加。在总体样本中有两种健康行为起到了中介作用：体重指数和运动。这些发现表明，积极情感和生活满意度等PEWB因素在普通人群以及老年慢性病个体中均与HbA1c相关。体重指数和适度运动等健康因素介导了这种关系。
