Adams M A, Hutton W C
Spine (Phila Pa 1976). 1985 Jul-Aug;10(6):524-31. doi: 10.1097/00007632-198507000-00006.
Fifty-two cadaveric lumbar motion segments were subjected to fatigue loading in compression and bending to determine if the intervertebral discs could prolapse in a gradual manner. Prior to testing, the nucleus pulposus of each disc was stained with a small quantity of blue dye and radiopaque solution. This enabled the progress of any gradual prolapse to be monitored by direct observation and by discogram. Six discs developed a gradual prolapse during the testing period. The injury starts with the lamellae of the annulus being distorted to form radial fissures and then nuclear pulp is extruded from the disc and leaks into the spinal canal. Discs most commonly affected were from the lower lumbar spine of young cadavers. Tests on ten older discs with pre-existing ruptures showed that such discs are stable and do not leak nuclear pulp.
对52个尸体腰椎运动节段进行压缩和弯曲疲劳加载试验，以确定椎间盘是否会逐渐突出。在测试前，每个椎间盘的髓核用少量蓝色染料和不透射线溶液染色。这使得可以通过直接观察和椎间盘造影来监测任何逐渐突出的进展情况。在测试期间，有6个椎间盘出现了逐渐突出。损伤始于纤维环的薄片扭曲形成放射状裂缝，然后髓核从椎间盘中挤出并渗漏到椎管中。最常受影响的椎间盘来自年轻尸体的下腰椎。对10个已有破裂的老年椎间盘进行的测试表明，这些椎间盘是稳定的，不会渗漏髓核。
