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肾上皮样血管平滑肌脂肪瘤的影像学特征及其与风险分层的相关性。

Imaging characteristics of renal epithelioid angiomyolipoma and its correlation with risk stratification.

作者信息

Zhou Jin, Qin Guo-Chu, Chen Ting-Ting, Cheng Le, Zhu Li

机构信息

Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210008, China.

Department of Pathology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, 210008, China.

出版信息

Sci Rep. 2025 Aug 17;15(1):30053. doi: 10.1038/s41598-025-15340-x.

Abstract

Renal epithelioid angiomyolipoma (EAML) is frequently misdiagnosed due to nonspecific imaging findings. This study aimed to explore the radiographic characteristics of EAML, with the goal of enhancing the accuracy of preoperative diagnoses. A total of 27 patients with histopathologically confirmed renal EAML were included in the study. We retrospectively reviewed the radiographic features and analyzed the differences between tumors with a cut-off diameter of 40 mm. The majority of the lesions were isolated (25/27, 92.59%) and were predominantly found in females (18/27, 66.67%). ‌CT images revealed that most lesions were hyperdense, with fat detected in 13 cases. Small lesions were more likely to exhibit rapid wash-in and wash-out enhancement (p = 0.04), whereas abnormal vessels were more commonly found in large lesions. Tumors with higher risk stratification tended to show persistent or delayed enhancement on CT images. The imaging manifestations of renal EAML are diverse. After enhancement, small lesions are more likely to display rapid wash-in and wash-out patterns on CT images, whereas large lesions are more likely to exhibit abnormal vessels within or surrounding the tumor.

摘要

肾上皮样血管平滑肌脂肪瘤(EAML)常因影像学表现不具特异性而被误诊。本研究旨在探讨EAML的影像学特征,以提高术前诊断的准确性。本研究共纳入27例经组织病理学确诊的肾EAML患者。我们回顾性分析了其影像学特征,并分析了直径40 mm以上肿瘤之间的差异。大多数病变为孤立性(25/27,92.59%),且主要见于女性(18/27,66.67%)。CT图像显示,大多数病变为高密度,13例检测到脂肪成分。较小病变更易表现为快速强化及快速廓清(p = 0.04),而较大病变中异常血管更为常见。风险分层较高的肿瘤在CT图像上往往表现为持续性或延迟性强化。肾EAML的影像学表现多样。增强后,较小病变在CT图像上更易表现为快速强化及快速廓清模式,而较大病变更易在肿瘤内部或周围出现异常血管。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e58f/12358567/8faeb88f0eed/41598_2025_15340_Fig1_HTML.jpg

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