Richard F, Renard L, Wambersie A
Strahlentherapie. 1985 Dec;161(12):794-6.
Between March 1978 and October 1983, 65 patients with locally advanced soft tissue sarcomas were treated at the cyclotron of Louvain-la-Neuve. 46 patients are analysed, 19 patients with intraabdominal or intrathoracic lesions are excluded. After "radical surgery" (no "gross tumour" present at the time of neutron therapy), a local control rate of 93% was achieved (25/27 patients) and the survival was 74%. In a second group of 19 patients with incompletely resected, or recurrent, or inoperable tumour, a local control was obtained in four cases (21%), and 13 patients were alive (69%). The follow-up ranged from three to 65 months (mean: 25,9 months). Ten severe complications were observed (22%); they were related to the field sizes, which reflected the local tumour extent.
1978年3月至1983年10月期间,65例局部晚期软组织肉瘤患者在鲁汶新镇的回旋加速器接受治疗。分析了46例患者,排除了19例有腹腔或胸腔病变的患者。在“根治性手术”(中子治疗时无“肉眼可见肿瘤”)后,局部控制率达到93%(27例患者中的25例),生存率为74%。在第二组19例肿瘤未完全切除、复发或无法手术的患者中,4例(21%)实现了局部控制,13例患者存活(69%)。随访时间为3至65个月(平均:25.9个月)。观察到10例严重并发症(22%);它们与照射野大小有关,这反映了局部肿瘤范围。