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经分期前后外侧联合整块脊椎切除术治疗胸椎假性肌源性血管内皮瘤:病例展示

Pseudomyogenic hemangioendothelioma in the thoracic spine treated with en bloc spondylectomy via staged anterior-lateral and posterior approach: illustrative case.

作者信息

Peng Sophia, Pearce Clairice, Sadeh Morteza, Abou-Mrad Tatiana, Borhani Martin, Mehta Ankit I

机构信息

Department of Neurosurgery, University of Illinois Chicago, Chicago, Illinois.

Department of Surgery, University of Illinois Chicago, Chicago, Illinois.

出版信息

J Neurosurg Case Lessons. 2025 Aug 18;10(7). doi: 10.3171/CASE25256.

DOI:10.3171/CASE25256
PMID:40825246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12362186/
Abstract

BACKGROUND

Pseudomyogenic hemangioendothelioma (PMHE) is a rare vascular tumor with intermediate malignant potential, most commonly affecting young males and typically involving the soft tissues of the lower extremities. Spinal involvement is exceedingly rare, particularly as an isolated bony lesion without soft tissue extension, posing challenges in establishing standardized treatment approaches.

OBSERVATIONS

This report details a unique case of thoracic PMHE in a 60-year-old woman managed with a multistaged surgical approach, including preoperative embolization and en bloc spondylectomy. The authors describe the patient's clinical presentation, radiographic findings, surgical technique, and postoperative course, highlighting the role of en bloc resection in achieving tumor control.

LESSONS

This case underscores the feasibility of aggressive surgical management for spinal PMHE and emphasizes the need for further research to refine optimal treatment strategies. https://thejns.org/doi/10.3171/CASE25256.

摘要

背景

假性肌源性血管内皮瘤(PMHE)是一种具有中等恶性潜能的罕见血管肿瘤,最常累及年轻男性,通常侵犯下肢软组织。脊柱受累极为罕见,尤其是作为孤立的骨病变且无软组织侵犯,这给制定标准化治疗方案带来了挑战。

观察结果

本报告详细介绍了一名60岁女性胸段PMHE的独特病例,采用了多阶段手术方法进行治疗,包括术前栓塞和整块椎体切除术。作者描述了患者的临床表现、影像学检查结果、手术技术和术后病程,强调了整块切除在实现肿瘤控制中的作用。

经验教训

该病例强调了积极手术治疗脊柱PMHE的可行性,并强调需要进一步研究以完善最佳治疗策略。https://thejns.org/doi/10.3171/CASE25256 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/e7288ff94e35/CASE25256_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/619266e8cf7a/CASE25256_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/b7d9e9cf2867/CASE25256_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/11965e7cd3f3/CASE25256_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/e7288ff94e35/CASE25256_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/619266e8cf7a/CASE25256_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/b7d9e9cf2867/CASE25256_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/11965e7cd3f3/CASE25256_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/12362186/e7288ff94e35/CASE25256_figure_4.jpg

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本文引用的文献

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Efficacy and safety of en-bloc resection versus debulking for spinal tumor: a systematic review and meta-analysis.整块切除与肿瘤减灭术治疗脊柱肿瘤的疗效和安全性:系统评价和荟萃分析。
World J Surg Oncol. 2024 Aug 3;22(1):208. doi: 10.1186/s12957-024-03494-3.
2
Revisiting En Bloc Resection Versus Piecemeal Resection for the Treatment of Giant Cell Tumor of the Spine.重新审视整块切除与分块切除治疗脊柱骨巨细胞瘤的疗效
World Neurosurg. 2023 Oct;178:e165-e173. doi: 10.1016/j.wneu.2023.07.016. Epub 2023 Jul 13.
3
Clinicopathological study of pseudomyogenic hemangioendothelioma.
假性肌源性血管内皮瘤的临床病理研究。
Diagn Pathol. 2023 Feb 20;18(1):25. doi: 10.1186/s13000-023-01309-9.
4
Pseudomyogenic hemangioendothelioma-A case report and review of the literature.假性肌源性血管内皮瘤——病例报告及文献综述
Radiol Case Rep. 2019 Aug 6;14(10):1228-1232. doi: 10.1016/j.radcr.2019.06.029. eCollection 2019 Oct.
5
Pseudomyogenic Hemangioendothelioma.假肌源性血管内皮瘤。
Arch Pathol Lab Med. 2019 Jun;143(6):763-767. doi: 10.5858/arpa.2017-0430-RS. Epub 2018 Dec 21.
6
Total spondylectomy.全脊椎切除术
J Spine Surg. 2018 Sep;4(3):663-665. doi: 10.21037/jss.2018.06.12.
7
Sirolimus therapy in the treatment of pseudomyogenic hemangioendothelioma.西罗莫司治疗假性肌源性血管内皮瘤
Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26781. Epub 2017 Aug 26.
8
Everolimus for Treatment of Pseudomyogenic Hemangioendothelioma.依维莫司治疗假性肌源性血管内皮瘤
J Pediatr Hematol Oncol. 2017 Aug;39(6):e328-e331. doi: 10.1097/MPH.0000000000000778.
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Eur Spine J. 2013 May;22 Suppl 3(Suppl 3):S506-11. doi: 10.1007/s00586-013-2727-3. Epub 2013 Feb 24.
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