抗μ链特异性免疫抑制对小鼠基孔肯雅病毒脑炎的影响。
Effect of anti-mu-chain-specific immunosuppression on Chikungunya virus encephalitis of mice.
作者信息
Giovarelli M, Viano I, Zucca M, Valbonesi R, Dianzani F
出版信息
Infect Immun. 1977 Jun;16(3):849-52. doi: 10.1128/iai.16.3.849-852.1977.
Abstract
Mice neonatally immunosuppressed with anti-mu antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently lower than non-immunosuppressed control mice. Several possible explanations for this finding are discussed.
摘要
新生期用抗μ抗血清进行免疫抑制的小鼠未能产生针对绵羊红细胞的循环抗体，且循环免疫球蛋白显著减少。然而，当它们脑内感染基孔肯雅病毒（一种甲群披膜病毒）时，其死亡率始终低于未免疫抑制的对照小鼠。本文讨论了这一发现的几种可能解释。
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Immunosuppression of mice injected with heterologous anti-immunoglobulin heavy chain antisera.注射异源抗免疫球蛋白重链抗血清的小鼠的免疫抑制
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Immunosuppression in mice injected with heterologous anti-immunoglobulin antisera.注射异种抗免疫球蛋白抗血清的小鼠中的免疫抑制。
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In vitro studies of cell-mediated immunity in an acute viral infection.
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