[Hypermyoglobinemia and creatine phosphokinase MB activity as signs of combined myocardial lesion and acute cerebral circulatory disorder].

In order to detect simultaneous damage to the myocardium in cerebral stroke the authors radioimmunoassayed myoglubin and activity of the heart fraction of creatine phosphokinase MB (CP K MB) in the blood serum of 22 patients. Hypermyoglobinemia and elevated activity of CP K MB were revealed in almost all cases of hemorrhagic stroke (15 patients) whereas in patients with ischemic stroke they were identified far less frequently. Thus, hypermyoglobinemia and the activity of CP K MB correlate with the macro- and microscopic picture of myocardial damage and may serve as its diagnostic criteria when both the clinical picture and ECG findings prove uninformative.