Li Qunzhen, Zhang Maoxiang, Cai Yanjuan, Zhuang Shutong
Department of Nutrition, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.
Department of Gastrointestinal Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.
Endocrine. 2025 Aug 19. doi: 10.1007/s12020-025-04370-0.
We aimed to research the effect of 6-week moderate- and low-intensity exercise combined with individualized nutrition interventions on the quality of life of obese, hypertensive adolescents.
One hundred and ten obese adolescents with hypertension were prospectively recruited for this study and were randomly divided into two groups: the control group (received routine intervention, n = 55) and the study group (received a 6-week moderate- and low-intensity exercise program combined with individualized nutritional intervention in addition to the control group's treatment, n = 55). Waist circumference, body mass index (BMI), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were measured before and 6 weeks after the intervention. The Screen for Child Anxiety Related Emotional Disorders (SCARED) and the Children's Depression Inventory (CDI) were used to assess the adolescents' mental health status, and the Pediatric Quality of Life Inventory (PedsQL) was used to evaluate their quality of life.
After the intervention, waist circumference, BMI, SBP, DBP, SCARED scores, and CDI scores decreased in both groups, while PedsQL subscale scores increased (all P < 0.05), with the study group showing lower waist circumference, BMI, SBP, DBP, SCARED scores, and CDI scores, and higher PedsQL scores than the control group (all P < 0.05).
The 6-week moderate- and low-intensity exercise combined with individualized nutritional intervention was found to effectively improve the quality of life of obese and hypertensive adolescents.
我们旨在研究为期6周的中等强度和低强度运动结合个性化营养干预对肥胖、高血压青少年生活质量的影响。
前瞻性招募110名肥胖高血压青少年参与本研究，并随机分为两组：对照组（接受常规干预，n = 55）和研究组（除接受对照组治疗外，还接受为期6周的中等强度和低强度运动计划及个性化营养干预，n = 55）。在干预前和干预6周后测量腰围、体重指数（BMI）、收缩压（SBP）和舒张压（DBP）。使用儿童焦虑相关情绪障碍筛查量表（SCARED）和儿童抑郁量表（CDI）评估青少年的心理健康状况，使用儿童生活质量量表（PedsQL）评估他们的生活质量。
干预后，两组的腰围、BMI、SBP、DBP、SCARED评分和CDI评分均下降，而PedsQL子量表评分升高（均P < 0.05），研究组的腰围、BMI、SBP、DBP、SCARED评分和CDI评分低于对照组，PedsQL评分高于对照组（均P < 0.05）。
发现为期6周的中等强度和低强度运动结合个性化营养干预可有效改善肥胖高血压青少年的生活质量。
