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Challenges and perspectives in traditional Chinese medicine intervention for uremic pruritus: emphasis on blinding, mechanisms, and safety assessment.

作者信息

Chen Songhe, Zhang Ying

机构信息

Gulou Subdistrict Community Health Center, Haishu District, Ningbo, 315000, Zhejiang, China.

Ningbo Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, No. 819, Liyuan North Road, Ningbo, 315000, Zhejiang, China.

出版信息

Int Urol Nephrol. 2025 Aug 19. doi: 10.1007/s11255-025-04742-5.

DOI:10.1007/s11255-025-04742-5
PMID:40828501
Abstract
摘要

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Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.整合代谢组学与网络药理学分析以揭示温肾阳汤治疗慢性肾脏病的机制
Front Pharmacol. 2025 Apr 30;16:1500463. doi: 10.3389/fphar.2025.1500463. eCollection 2025.
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AST-120 improved uremic pruritus by lowering indoxyl sulfate and inflammatory cytokines in hemodialysis patients.
AST-120 通过降低血液透析患者的硫酸吲哚酚和炎症细胞因子来改善尿毒症瘙痒。
Aging (Albany NY). 2024 Feb 21;16(5):4236-4249. doi: 10.18632/aging.205580.
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Huang Gan Formula Alleviates Systemic Inflammation and Uremia in Adenine-Induced Chronic Kidney Disease Rats May Associate with Modification of Gut Microbiota and Colonic Microenvironment.黄甘方缓解腺嘌呤诱导的慢性肾脏病大鼠全身炎症和尿毒症可能与肠道微生物群和结肠微环境的改变有关。
Drug Des Devel Ther. 2024 Jan 6;18:13-28. doi: 10.2147/DDDT.S421446. eCollection 2024.
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