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Finding a brush when you expect a broom: a novel model of paediatric Wilms tumour evolution.

作者信息

Hong Andrew L, Mullen Elizabeth A

机构信息

Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.

Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.

出版信息

Nat Rev Urol. 2025 Aug 19. doi: 10.1038/s41585-025-01082-y.

DOI:10.1038/s41585-025-01082-y
PMID:40830243
Abstract
摘要

相似文献

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BMJ Paediatr Open. 2025 Jul 24;9(1):e003396. doi: 10.1136/bmjpo-2025-003396.

本文引用的文献

1
High resolution clonal architecture of hypomutated Wilms tumours.低突变型肾母细胞瘤的高分辨率克隆结构
Nat Commun. 2025 May 29;16(1):4647. doi: 10.1038/s41467-025-59854-4.
2
Rare germline structural variants increase risk for pediatric solid tumors.罕见的种系结构变异会增加儿童实体瘤的风险。
Science. 2025 Jan 3;387(6729):eadq0071. doi: 10.1126/science.adq0071.
3
Tumour mutational burden: clinical utility, challenges and emerging improvements.肿瘤突变负担：临床实用性、挑战和新兴的改进。
Nat Rev Clin Oncol. 2024 Oct;21(10):725-742. doi: 10.1038/s41571-024-00932-9. Epub 2024 Aug 27.
4
Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers.综合分析突变特征揭示了 27 种儿科癌症中的不同模式和分子过程。
Nat Cancer. 2023 Feb;4(2):276-289. doi: 10.1038/s43018-022-00509-4. Epub 2023 Jan 26.
5
FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits.FOXR2 是一种受表观遗传调控的泛癌致癌基因，可激活 ETS 转录回路。
Cancer Res. 2022 Sep 2;82(17):2980-3001. doi: 10.1158/0008-5472.CAN-22-0671.
6
Tumor Mutational Burden as a Predictive Biomarker in Solid Tumors.肿瘤突变负荷作为实体瘤的预测性生物标志物。
Cancer Discov. 2020 Dec;10(12):1808-1825. doi: 10.1158/2159-8290.CD-20-0522. Epub 2020 Nov 2.
7
The landscape of genomic alterations across childhood cancers.儿童癌症中基因组改变的全景。
Nature. 2018 Mar 15;555(7696):321-327. doi: 10.1038/nature25480. Epub 2018 Feb 28.
8
A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.儿童肿瘤学组和TARGET计划对肾母细胞瘤的基因图谱进行探索。
Nat Genet. 2017 Oct;49(10):1487-1494. doi: 10.1038/ng.3940. Epub 2017 Aug 21.
9
Detection of ultra-rare mutations by next-generation sequencing.通过下一代测序检测超罕见突变。
Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14508-13. doi: 10.1073/pnas.1208715109. Epub 2012 Aug 1.