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75至105岁女性中力量训练、步行和久坐与跌倒风险的关系:妇女健康倡议强壮与健康(WHISH)干预队列中的一项横断面研究。

Fall risk in relation to strength training, walking, and sitting among women aged 75-105 years: a cross-sectional study within the Women's Health Initiative Strong and Healthy (WHISH) Intervention Cohort.

作者信息

Rovzar Corey, Jhandi Saachi, Mackey Sally, Laddu Deepika, Shen Sa, LaCroix Andrea, Stefanick Marcia L

机构信息

Stanford University School of Medicine.

University of Utah School of Medicine.

出版信息

Res Sq. 2025 Aug 13:rs.3.rs-7246621. doi: 10.21203/rs.3.rs-7246621/v1.

Abstract

BACKGROUND

Falls are the leading cause of injury and injury death among older women in the United States. The Women's Health Initiative Strong and Healthy () trial intervention cohort provided the opportunity to assess how fall risk classification (FR-ABC), as measured by balance confidence, relates to strength training, walking, sitting, and physical function (PF) in women aged 75 and over, a growing population at particularly high fall risk.

METHODS

We analyzed data from 8,915 women aged 75-105 years (mean age 84.9 ± 5.1 years; 49.6% ≥85 years) randomly assigned to a PA intervention in the pragmatic trial. Participants self-reported their weekly participation in strength training, walking, daily sitting time, and current PF. Balance confidence was measured using the Activities-specific Balance Confidence (ABC) scale, with an ABC score of < 67% used to classify FR-ABC. We assessed FR-ABC prevalence in the total cohort and for the women aged 75-84 and 85 years and older and cross-sectional associations with strength training, walking, sitting, and PF categories using analysis of variance (ANOVA) and chi-squared tests.

RESULTS

Mean age was 84.9 years, with 49.6% of participants aged ≥ 85 years. FR-ABC classification was 35.1% overall, 22.7% for women aged 75-84 and 47.4% for women aged ≥ 85 years. Overall, strength training ≥ 2 hours per week was associated with a 34% FR-ABC risk reduction (RR = 0.66, 95% CI: 0.61-0.71); walking ≥ 4.25 hours/week with a 70% FR-ABC risk reduction (RR = 0.30, 95% CI: 0.27-0.33); while, sitting ≥ 8 hours/day was associated with a 41% increased FR-ABC risk (RR = 1.41, 95% CI: 1.33-1.49). High PF (score ≥ 90) was associated with a 91% FR-ABC risk reduction (p < 0.001).

CONCLUSION

More strength training and walking, lower sitting time, and higher PF were strongly associated with reduced fall risk classification among women aged 75 years and older. Although these associations were more pronounced among women aged 75-84 year, it was also true for women aged 85 and over. Fall risk prevention should emphasize each of these PA factors.

摘要

背景

在美国,跌倒 是老年女性受伤和因伤死亡的主要原因。女性健康倡议“强壮且健康”(WHI-SHW)试验干预队列提供了一个机会,来评估通过平衡信心衡量的跌倒风险分类(FR-ABC)与 75 岁及以上女性的力量训练、步行、坐姿和身体功能(PF)之间的关系,这一年龄段的女性跌倒风险尤其高且人数不断增加。

方法

我们分析了实用试验中随机分配到体力活动干预组的 8915 名 75 - 105 岁女性(平均年龄 84.9 ± 5.1 岁;49.6% ≥85 岁)的数据。参与者自行报告她们每周参与力量训练、步行的情况、每日坐姿时间和当前的身体功能。使用特定活动平衡信心(ABC)量表测量平衡信心,ABC 得分 < 67% 用于分类 FR-ABC。我们评估了整个队列以及 75 - 84 岁和 85 岁及以上女性的 FR-ABC 患病率,并使用方差分析(ANOVA)和卡方检验分析了与力量训练、步行、坐姿和 PF 类别之间的横断面关联。

结果

平均年龄为 84.9 岁,49.6% 的参与者年龄≥85 岁。总体 FR-ABC 分类率为 35.1%,75 - 84 岁女性为 22.7%,≥85 岁女性为 47.4%。总体而言,每周力量训练≥2 小时可使 FR-ABC 风险降低 34%(RR = 0.66,95% CI:0.61 - 0.71);每周步行≥4.25 小时可使 FR-ABC 风险降低 70%(RR = 0.30,95% CI:0.27 - 0.33);而每天坐姿≥8 小时会使 FR-ABC 风险增加 41%(RR = 1.41,95% CI:1.33 - 1.49)。高身体功能(得分≥90)与 FR-ABC 风险降低 91% 相关(p < 0.001)。

结论

更多的力量训练和步行、更短的坐姿时间以及更高的身体功能与 75 岁及以上女性跌倒风险分类降低密切相关。尽管这些关联在 75 - 84 岁女性中更为明显,但在 85 岁及以上女性中也是如此。预防跌倒风险应强调这些体力活动因素中的每一个。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56db/12363929/5e869cebd7dd/nihpp-rs7246621v1-f0001.jpg

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