Fan Qing, Yu Shuang, Sun Xu, Dong Yao, Chen Yao, Jia Lihong
Department of Nursing, First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China.
Department of Ophthalmology, The Third People's Hospital of Dalian, Dalian, People's Republic of China.
Psychol Res Behav Manag. 2025 Aug 12;18:1729-1747. doi: 10.2147/PRBM.S533200. eCollection 2025.
Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes. It has a slow and insidious onset, mainly manifested as sensory and motor dysfunction, and increases susceptibility to psychological problems such as anxiety and depression, seriously affecting the quality of life of patients. The current treatment strategies focus on effective metabolic management and lifestyle intervention, but the results are not satisfactory. Mindfulness therapy (MBT), as a non-pharmaceutical intervention method, has gradually shown potential value in the treatment of DPN. This review incorporates studies on the two in recent years, revealing the main mechanism by which MBT affects neuropsychology. It explores the feasibility and application status of MBT in reshaping the cognitive experience of pain in patients with DPN, alleviating pain perception, improving psychological states such as anxiety and depression, and thereby enhancing the overall quality of life. In conclusion, our research provides more powerful evidence for the clinical treatment of patients with DPN by applying MBT.
糖尿病周围神经病变（DPN）是糖尿病最常见的慢性并发症之一。其起病缓慢且隐匿，主要表现为感觉和运动功能障碍，并增加了焦虑和抑郁等心理问题的易感性，严重影响患者的生活质量。目前的治疗策略侧重于有效的代谢管理和生活方式干预，但效果并不理想。正念疗法（MBT）作为一种非药物干预方法，在DPN的治疗中逐渐显示出潜在价值。本综述纳入了近年来关于二者的研究，揭示了MBT影响神经心理学的主要机制。它探讨了MBT在重塑DPN患者疼痛认知体验、减轻疼痛感知、改善焦虑和抑郁等心理状态从而提高整体生活质量方面的可行性和应用现状。总之，我们的研究为应用MBT临床治疗DPN患者提供了更有力的证据。
