Tóth T
Int Urol Nephrol. 1985;17(2):119-25. doi: 10.1007/BF02082481.
The author reports on a case of renal oncocytoma, showing up as a side finding during autopsy. In the light microscopic picture of the tumour typical tubular alveolar, in some places solid arrangement was observed. The cytoplasm of the tumour cells could be characterized by even, subtle granulation. Malignant transformation was detected. It has been proved by electron microscopic examination that the granular appearance of the cytoplasm originated from mitochondria. In the light of the literary data the author underlines the rarity and the diagnostical importance of the alteration. Oncocytoma should be distinguished from granular, cellular cancer of the kidney and from malignant oncocytoma.
作者报告了一例肾嗜酸细胞瘤,该病例是在尸检时作为附带发现出现的。在肿瘤的光学显微镜图像中,观察到典型的管状肺泡结构,在某些部位呈实性排列。肿瘤细胞的细胞质具有均匀、细微的颗粒状特征。检测到恶性转化。电子显微镜检查证实,细胞质的颗粒状外观源于线粒体。根据文献资料,作者强调了这种改变的罕见性和诊断重要性。嗜酸细胞瘤应与肾颗粒细胞癌和恶性嗜酸细胞瘤相鉴别。