两种茶碱控释制剂的研究。
Study of two controlled-release theophylline preparations.
作者信息
Fink J N, Levy M B, Conrad E
出版信息
Am J Med. 1985 Dec 20;79(6A):58-61. doi: 10.1016/0002-9343(85)90090-7.
PMID:4083301
Abstract
Two sustained-release theophylline preparations, one a 12-hour and the other a 24-hour product, were compared in 20 subjects with stable asthma. All patients had good control of symptoms, and the calculated pharmacokinetic parameters were comparable for both drugs. The 24-hour sustained-release preparation can thus be utilized in the therapy of asthma.
摘要
在20名患有稳定型哮喘的受试者中比较了两种缓释茶碱制剂，一种是12小时的产品，另一种是24小时的产品。所有患者的症状都得到了良好控制，两种药物的计算药代动力学参数相当。因此，24小时缓释制剂可用于哮喘治疗。
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