Shrikant Sundari, Jain Anshul
Director, Department of Internal Medicine, Accord Superspeciality Hospital, Faridabad, Haryana, India, Corresponding Author, Orcid: https://orcid.org/0009-0003-3017-2372.
Post Graduate 3rd Year, Department of Internal Medicine, Marengo Asia Hospitals, Faridabad, Haryana, India.
J Assoc Physicians India. 2025 Jul;73(7S):47-49. doi: 10.59556/japi.73.0980.
A 46-year-old male nonsmoker presented to the outpatient department (OPD) with a history of progressively increasing breathlessness and central cyanosis since 1 month. He had a history of surgery for craniopharyngioma 6 years back and was on hormone replacement therapy. On evaluation, no cardiopulmonary cause was found for cyanosis. Patient was detected to have cirrhosis, possibly due to nonalcoholic fatty liver disease (NAFLD), and hepatopulmonary syndrome (HPS) was suspected as the cause for dyspnea and cyanosis, which was confirmed on workup. HPS as the first presentation of undiagnosed cirrhosis is relatively rare, although there are some case reports in the literature.
一名46岁不吸烟男性因自1个月以来进行性加重的呼吸困难和中央性发绀就诊于门诊。他6年前有颅咽管瘤手术史，目前正在接受激素替代治疗。经评估，未发现导致发绀的心肺病因。患者被检测出患有肝硬化，可能是由于非酒精性脂肪性肝病（NAFLD），并怀疑肝肺综合征（HPS）是呼吸困难和发绀的原因，检查后得以证实。HPS作为未确诊肝硬化的首发表现相对罕见，尽管文献中有一些病例报告。
