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经正中胸骨切开术切除纵隔肿物:病因不明的胸腺瘤。

Median Sternotomy for Mediastinal Mass Removal: Thymoma of Unknown Cause.

作者信息

Murphy Kaitlin N, Hoodfar Arian, Katkic Mitchell, Purut Cemil

机构信息

Internal Medicine, Edward Via College of Osteopathic Medicine (VCOM), Roanoke, USA.

Research, Edward Via College of Osteopathic Medicine (VCOM), Blacksburg, USA.

出版信息

Cureus. 2025 Jul 20;17(7):e88364. doi: 10.7759/cureus.88364. eCollection 2025 Jul.

DOI:10.7759/cureus.88364
PMID:40837899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12363424/
Abstract

Thymoma is a rare mediastinal malignancy. Although it may often be associated with paraneoplastic syndromes such as hypogammaglobulinemia, pure red cell aplasia, or myasthenia gravis (MG), some thymomas may also be idiopathic in origin. Although thymoma is the most common mass found in the anterior mediastinum, its rarity still proves difficult in swift diagnosis and subsequent treatment. This case presents a patient with an unknown anterior mediastinal mass incidentally found on imaging, with the final diagnosis of thymoma made from a pathologic investigation that was performed post-sternotomy and resection.

摘要

胸腺瘤是一种罕见的纵隔恶性肿瘤。尽管它常与副肿瘤综合征相关,如低丙种球蛋白血症、纯红细胞再生障碍或重症肌无力(MG),但一些胸腺瘤也可能起源不明。虽然胸腺瘤是前纵隔中最常见的肿块,但其罕见性仍使得快速诊断及后续治疗颇具难度。本病例介绍了一名患者,其在影像学检查中偶然发现前纵隔有一不明肿块,最终通过胸骨切开术和切除术后的病理检查确诊为胸腺瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/174577e2d6df/cureus-0017-00000088364-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/17f671f147ed/cureus-0017-00000088364-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/87a6adaf654b/cureus-0017-00000088364-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/174577e2d6df/cureus-0017-00000088364-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/17f671f147ed/cureus-0017-00000088364-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/87a6adaf654b/cureus-0017-00000088364-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ac5/12363424/174577e2d6df/cureus-0017-00000088364-i03.jpg

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本文引用的文献

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A systematic review of paraneoplastic syndromes associated with thymoma: Treatment modalities, recurrence, and outcomes in resected cases.胸腺瘤相关副肿瘤综合征的系统评价:切除病例的治疗方式、复发和结局。
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基于中国胸腺瘤研究联盟回顾性数据库,比较Masaoka-Koga分期与国际肺癌研究协会/国际胸腺恶性肿瘤兴趣小组提出的TNM分期系统。
J Thorac Dis. 2016 Apr;8(4):727-37. doi: 10.21037/jtd.2016.03.22.
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Paraneoplastic disorders in thymoma patients.胸腺瘤患者的副肿瘤性疾病。
J Thorac Oncol. 2014 Sep;9(9 Suppl 2):S143-7. doi: 10.1097/JTO.0000000000000300.
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Thymoma: current diagnosis and treatment.胸腺瘤:当前的诊断与治疗。
Chin Med J (Engl). 2013;126(11):2186-91.
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Role of imaging in the diagnosis, staging, and treatment of thymoma.影像在胸腺瘤的诊断、分期和治疗中的作用。
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Hum Pathol. 1993 Sep;24(9):958-69. doi: 10.1016/0046-8177(93)90109-t.
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Thymoma: results of 241 operated cases.胸腺瘤:241例手术病例的结果
Ann Thorac Surg. 1991 Jan;51(1):152-6. doi: 10.1016/0003-4975(91)90478-9.