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[荷瘤小鼠对胎鼠组织3M氯化钾提取物的淋巴细胞反应性:去除含肿瘤细胞的扩散小室可逆转该反应性]

[Lymphocyte reactivity of tumor-bearing mice to a 3M KCl extract of fetal mouse tissue: removal of diffusion chambers containing tumor cells reverses the reactivity].

作者信息

Albrecht S, Gryschek G, Schlott B, Pasternak G

出版信息

Arch Geschwulstforsch. 1985;55(6):451-6.

PMID:4084000
Abstract

Sensitization of lymphocytes to 3M KCl fetal extracts was shown by the MEM test after diffusion chambers containing tumor cells have been implanted into mice. Lymphocyte reactivity was still present 2, 4 and 6 weeks after removal of the chambers. When tested after 9 and 12 weeks the sensitization was no longer detectable. This results show the reversibility of sensitization after complete removal of tumor cells.

摘要

在将含有肿瘤细胞的扩散室植入小鼠体内后,通过MEM试验显示淋巴细胞对3M KCl胎儿提取物产生了致敏作用。在移除扩散室2、4和6周后,淋巴细胞反应性仍然存在。在9周和12周后进行测试时,致敏作用不再可检测到。这些结果表明在完全去除肿瘤细胞后致敏作用具有可逆性。

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