Claudel Jean-Paul, Ballanger Fabienne, Auffret Nicole, Leccia Marie-Thérèse, Dréno Brigitte
Private practice, Tours, France.
Private practice, Talence, France.
Acta Derm Venereol. 2025 Aug 21;105:adv43945. doi: 10.2340/actadv.v105.43945.
Acne vulgaris is an inflammatory and multifactorial skin disease involving the sebaceous gland and the skin microbiome. Different exposome factors, including hormonal and family factors, have been suggested to influence acne. Obesity is an increasingly observed condition worldwide, and is considered as a public health problem by the World Health Organization. Recently, a high body mass index has been identified as an acne severity risk factor in adolescents. A group of 5 dermatologists from different institutions and private practices from France involved in the research and clinical fields of acne -analysed recent literature on "obesity and acne" focusing on epidemiology, the pathogenesis of acne and obesity, as well as the management of acne in obese patients. The authors selected, prior to their discussion in November and December 2024 and again in March 2025, and discussed 52 articles concerning acne and obesity published since 2000 and available from the PubMed database. The authors agreed that, considering these common metabolic features, managing both acne and obesity in parallel and helping patients through a global approach including dermatological, endocrinal, psychological and nutrition, as well as lifestyle support is mandatory, and may allow for the improvement of both acne and obesity. Moreover, in order to allow dermatologists to manage acne in obese patients in the most efficient way, the authors developed and propose a decision tree. The authors consider that acne in obese patients is not a fatality, and taking care of acne should not be considered an isolated task in this specific patient population.
寻常痤疮是一种涉及皮脂腺和皮肤微生物群的炎症性多因素皮肤病。不同的暴露组因素，包括激素和家族因素，被认为会影响痤疮。肥胖在全球范围内的发病率日益上升，世界卫生组织将其视为一个公共卫生问题。最近，高体重指数已被确定为青少年痤疮严重程度的一个风险因素。来自法国不同机构和私人诊所的5名皮肤科医生组成的团队，他们参与了痤疮的研究和临床领域，分析了关于“肥胖与痤疮”的最新文献，重点关注流行病学、痤疮和肥胖的发病机制，以及肥胖患者痤疮的管理。作者在2024年11月和12月以及2025年3月进行讨论之前进行了筛选，并讨论了自2000年以来发表的、可从PubMed数据库获取的52篇关于痤疮和肥胖的文章。作者一致认为，考虑到这些共同的代谢特征，同时管理痤疮和肥胖，并通过包括皮肤科、内分泌科、心理科和营养科以及生活方式支持在内的综合方法帮助患者是必不可少的，这可能会改善痤疮和肥胖状况。此外，为了让皮肤科医生以最有效的方式管理肥胖患者的痤疮，作者制定并提出了一个决策树。作者认为肥胖患者的痤疮并非不治之症，在这一特定患者群体中，治疗痤疮不应被视为一项孤立的任务。
