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中药通过肠道微生物群调节多囊卵巢综合征的机制:综述

Mechanisms of traditional Chinese medicine regulating polycystic ovary syndrome through gut microbiota: a review.

作者信息

Jiang Xiaomei, Wang Yongfeng, Hua Yu, Tang Hong, Li Heyue

机构信息

Department of Gynecology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.

出版信息

Front Endocrinol (Lausanne). 2025 Aug 6;16:1610869. doi: 10.3389/fendo.2025.1610869. eCollection 2025.

Abstract

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder that adversely affects women's reproductive and metabolic health conditions. Recent studies have highlighted the significant contributory role of gut microbiota in the pathogenesis of PCOS, indicating a complex interplay between the microbiome and the syndrome's clinical manifestations. Given this connection, Traditional Chinese Medicine (TCM), a well-established therapeutic approach, has demonstrated potential efficacy in modulating gut microbiota and alleviating symptoms associated with PCOS. This review aims to summarize and analyze current research on the effects of TCM on gut microbiota in individuals with PCOS, exploring underlying mechanisms and relevant findings to provide insights for future clinical applications and improve understanding of TCM's role in managing PCOS.

摘要

多囊卵巢综合征(PCOS)是一种常见的内分泌紊乱疾病,对女性的生殖和代谢健康状况产生不利影响。最近的研究强调了肠道微生物群在PCOS发病机制中的重要作用,表明微生物群与该综合征的临床表现之间存在复杂的相互作用。鉴于这种联系,传统中医(TCM)作为一种成熟的治疗方法,已显示出在调节肠道微生物群和缓解PCOS相关症状方面的潜在疗效。本综述旨在总结和分析目前关于中医对PCOS患者肠道微生物群影响的研究,探索潜在机制和相关发现,为未来的临床应用提供见解,并增进对中医在管理PCOS中作用的理解。

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