经口抗反流折叠术：腹腔镜袖状胃成形术后难治性胃食管反流病的一种新方法。
Transoral antireflux plication: a new approach for refractory GERD after laparoscopic sleeve gastroplasty.
作者信息
Bachu Vismaya S, Quon Cameron, Lee Anna H, Alhanaee Manar, Issa Danny
机构信息
Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Vatche & Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
出版信息
VideoGIE. 2025 Apr 5;10(9):475-478. doi: 10.1016/j.vgie.2025.04.002. eCollection 2025 Sep.
BACKGROUND AND AIMS
New-onset GERD is a common adverse event after laparoscopic sleeve gastrectomy (LSG), with limited treatment options beyond medical therapy or surgical conversion. This case study presents a minimally invasive endoscopic approach-transoral antireflux plication (TARP)-for managing post-LSG GERD.
METHODS
A 54-year-old woman with refractory GERD post-LSG underwent endoscopic sleeve revision and TARP. The procedure involved submucosal injection, mucosal incision, and full-thickness endoscopic suturing to reduce gastric volume and create an antireflux barrier.
RESULTS
A pH monitoring study 1 month postprocedure showed significant improvement in reflux parameters and symptom relief, independent of weight loss.
CONCLUSIONS
TARP with endoscopic sleeve revision may offer a safe, minimally invasive alternative to surgery for post-LSG GERD. Further research is needed to confirm long-term efficacy and patient selection criteria.
背景与目的
新发胃食管反流病（GERD）是腹腔镜袖状胃切除术（LSG）后常见的不良事件，除药物治疗或手术改道外，治疗选择有限。本病例研究介绍了一种用于治疗LSG术后GERD的微创内镜方法——经口抗反流折叠术（TARP）。
方法
一名54岁的LSG术后难治性GERD女性患者接受了内镜袖状修复术和TARP。该手术包括黏膜下注射、黏膜切开和全层内镜缝合，以减少胃容积并建立抗反流屏障。
结果
术后1个月的pH监测研究显示，反流参数显著改善，症状缓解，且与体重减轻无关。
结论
TARP联合内镜袖状修复术可能为LSG术后GERD提供一种安全、微创的手术替代方案。需要进一步研究以证实其长期疗效和患者选择标准。
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