Kamysz Wojciech, Kleczkowska Patrycja
Department of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Gdansk, 80-416 Gdansk, Poland.
Department of Biomedical Research, National Medicines Institute, 00-725 Warsaw, Poland.
Med Sci (Basel). 2025 Aug 1;13(3):106. doi: 10.3390/medsci13030106.
Wound care in military and combat environments poses distinct challenges that set it apart from conventional medical practice in civilian settings. The nature of injuries sustained on the battlefield-often complex, contaminated, and involving extensive tissue damage-combined with limited access to immediate medical intervention, significantly increases the risk of infection, delayed healing, and adverse outcomes. Traditional wound dressings frequently prove inadequate under such extreme conditions, as they have not been designed to address the specific physiological and logistical constraints present during armed conflicts. This review provides a comprehensive overview of recent progress in the development of advanced wound dressings tailored for use in military scenarios. Special attention has been given to multifunctional dressings that go beyond basic wound coverage by incorporating biologically active macromolecules such as collagen, chitosan, thrombin, alginate, therapeutic peptides, and growth factors. These compounds contribute to properties including moisture balance control, exudate absorption, microbial entrapment, and protection against secondary infection. This review highlights the critical role of advanced wound dressings in improving medical outcomes for injured military personnel. The potential of these technologies to reduce complications, enhance healing rates, and ultimately save lives underscores their growing importance in modern battlefield medicine.
军事和战斗环境中的伤口护理带来了独特的挑战，使其有别于民用环境中的传统医疗实践。战场上遭受的损伤往往复杂、受污染且涉及广泛的组织损伤，再加上难以立即获得医疗干预，这显著增加了感染、愈合延迟和不良后果的风险。在这种极端条件下，传统伤口敷料往往显得不足，因为它们并非为应对武装冲突期间存在的特定生理和后勤限制而设计。本综述全面概述了为军事场景量身定制的先进伤口敷料的最新进展。特别关注了多功能敷料，这些敷料通过纳入生物活性大分子如胶原蛋白、壳聚糖、凝血酶、藻酸盐、治疗性肽和生长因子，超越了基本的伤口覆盖功能。这些化合物有助于实现包括水分平衡控制、渗出液吸收、微生物截留以及预防二次感染等特性。本综述强调了先进伤口敷料在改善受伤军事人员医疗结局方面的关键作用。这些技术在减少并发症、提高愈合率并最终挽救生命方面的潜力凸显了它们在现代战场医学中日益重要的地位。
