Moradifar F, Sepahdoost N, Tavakoli P, Mirzapoor A
Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box 14115-154, Tehran, Iran.
Advanced and Smart Nanobiosystems Lab, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Heliyon. 2024 Dec 24;11(1):e41465. doi: 10.1016/j.heliyon.2024.e41465. eCollection 2025 Jan 15.
Considerable research has focused on advanced wound dressing technology over the past decade. The increasing emphasis on health and medical treatment is crucial to the modern healthcare system. Consequently, high-quality wound dressings with advanced standards are essential for superior medical care. Next-generation multifunctional wound dressings feature antibacterial properties, pain relief, biocompatibility, drug delivery, flexibility, and exudate absorption. Today, biomimetic models, tissue engineering, and synthetic skin are integrated with emerging wound healing technologies, offering a new perspective on wound management. Based on the classification model of multifunctional and advanced wound dressings, various AI-assisted wound management technologies are also highly efficient. The primary goals of advanced wound dressing technologies include faster wound healing, prevention of microbial contamination, preservation of skin aesthetics, reduction of treatment costs, and increased patient comfort. The latest technologies in this field not only promote faster healing and the treatment of deep wounds but also emphasize continuous control and monitoring of the healing process. These screenable wound dressings can be smart sensors to detect wound status based on parameters such as pH, moisture, temperature, and oxygen levels. This enables wound status monitoring and appropriate treatment responses. These technologies facilitate wound observation and monitoring, as well as the evaluation and control of the healing process through various models and strategies, such as the fabrication of functional nanomaterials, computer algorithms, and artificial intelligence. This review presents an overview of the most prominent new technologies in wound dressings, along with their innovative approaches.
在过去十年中，大量研究聚焦于先进的伤口敷料技术。对健康和医疗治疗的日益重视对现代医疗体系至关重要。因此，具有先进标准的高质量伤口敷料对于优质医疗护理必不可少。下一代多功能伤口敷料具有抗菌特性、缓解疼痛、生物相容性、药物递送、柔韧性和渗出液吸收等功能。如今，仿生模型、组织工程和合成皮肤与新兴的伤口愈合技术相结合，为伤口管理提供了新的视角。基于多功能和先进伤口敷料的分类模型，各种人工智能辅助的伤口管理技术也非常高效。先进伤口敷料技术的主要目标包括更快的伤口愈合、预防微生物污染、保持皮肤美观、降低治疗成本以及提高患者舒适度。该领域的最新技术不仅促进更快的愈合和深部伤口的治疗，还强调对愈合过程的持续控制和监测。这些可筛查的伤口敷料可以是智能传感器，根据pH值、湿度、温度和氧气水平等参数检测伤口状态。这能够实现伤口状态监测和适当的治疗反应。这些技术通过各种模型和策略，如功能性纳米材料的制备、计算机算法和人工智能，促进伤口观察和监测，以及对愈合过程的评估和控制。本综述概述了伤口敷料中最突出的新技术及其创新方法。
