Czeizel A, Métneki J
Acta Paediatr Hung. 1985;26(3):175-85.
Pregnancy outcomes of 546 women seeking advice for exposure to suspected dangerous environmental factors during pregnancy were analysed. Induced abortion was recommended to 58 women, and this advice was followed by 55 of them. An additional 24 pregnancies were interrupted. The rates of fetal death (spontaneous abortion, stillbirth and infant death) in the non-terminated pregnancies corresponded to national figures. The proportion of birth defects among the liveborn infants of women exposed to hazardous physical, chemical, microbial and maternal factors was 5/67 (7.5%), 11/120 (9.2%), 6/158 (3.8%) and 1/22 (4.5%), respectively. These figures did not differ significantly from the expected ones based on the Hungarian registered and estimated figures. Furthermore, a causal relation between the environmental factors and the defects could be excluded in all but one case in which there was exposure to a high dose of oestrogen.
对546名在孕期接触疑似危险环境因素并寻求建议的女性的妊娠结局进行了分析。向58名女性建议人工流产，其中55名接受了该建议。另有24例妊娠被终止。未终止妊娠中的胎儿死亡（自然流产、死产和婴儿死亡）率与全国数据相符。接触有害物理、化学、微生物和母体因素的女性所生活产婴儿中出生缺陷的比例分别为5/67（7.5%）、11/120（9.2%）、6/158（3.8%）和1/22（4.5%）。这些数字与基于匈牙利登记和估计数据的预期数字没有显著差异。此外，除了1例接触高剂量雌激素的情况外，在所有其他病例中均可排除环境因素与缺陷之间的因果关系。
