Garcia-Diaz D E, Aguilar-Baturoni H U, Guevara-Aguilar R, Wayner M J
Brain Res Bull. 1985 Dec;15(6):661-4. doi: 10.1016/0361-9230(85)90216-3.
Single unit discharges in the olfactory bulb (OB) were recorded extracellularly in anesthetized rats during controlled gastric distension. The activity of 37 neurons in the periglomerular layer of the OB modulated by gastric distension was analyzed. Twelve of the 37 cells decreased, eight decreased and then increased in frequency, and 17 displayed more complex effects due to gastric distension. Generally, the latency of the responses to gastric distension was less than one second. All those cells which responded to gastric distension also responded to vagus nerve stimulation. This effect was abolished or attenuated by cutting the vagus nerve at the cervical level. The threshold volume by which the stomach was infused for the initial decrease in OB neuronal discharge frequency was 3.0 ml. When more than 8 ml were infused, increases in firing frequencies were always observed. The results of the present experiments indicate that the discharge frequency of the periglomerular OB neurons are modulated by visceral afferents.
在麻醉大鼠进行控制性胃扩张期间，细胞外记录嗅球（OB）的单单位放电。分析了37个受胃扩张调节的OB小球周围层神经元的活动。37个细胞中有12个放电频率降低，8个先降低后升高，17个由于胃扩张表现出更复杂的效应。一般来说，对胃扩张反应的潜伏期小于1秒。所有对胃扩张有反应的细胞也对迷走神经刺激有反应。在颈部切断迷走神经后，这种效应被消除或减弱。引起OB神经元放电频率最初降低的胃内灌注阈值体积为3.0毫升。当灌注超过8毫升时，总是观察到放电频率增加。本实验结果表明，OB小球周围层神经元的放电频率受内脏传入神经调节。
