van Asperen P P, Gleeson M, Kemp A S, Cripps A W, Geraghty S B, Mellis C M, Clancy R L
Clin Exp Immunol. 1985 Dec;62(3):753-7.
In a prospective study, infants born to atopic parents had a significantly higher prevalence of salivary IgA deficiency at all ages studied than control infants, and the mean non zero IgA level of the potentially atopic infants was significantly lower at 8 and 12 months than of control infants. Of the infants with atopic parents, the prevalence of IgA deficiency was not significantly greater in those who manifested atopic disease during the study period than in those who did not, but the levels were significantly lower at 4 months.
在一项前瞻性研究中,患有特应性疾病的父母所生婴儿在所有研究年龄阶段的唾液 IgA 缺乏患病率均显著高于对照婴儿,并且在 8 个月和 12 个月时,潜在特应性婴儿的平均非零 IgA 水平显著低于对照婴儿。在患有特应性疾病的父母所生婴儿中,在研究期间出现特应性疾病的婴儿的 IgA 缺乏患病率并不显著高于未出现特应性疾病的婴儿,但在 4 个月时其水平显著较低。